ID A7RNY2_NEMVE Unreviewed; 906 AA.
AC A7RNY2;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EDO46759.1};
GN ORFNames=NEMVEDRAFT_v1g199903 {ECO:0000313|EMBL:EDO46759.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO46759.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO46759.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00460}.
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DR EMBL; DS469524; EDO46759.1; -; Genomic_DNA.
DR RefSeq; XP_001638822.1; XM_001638772.1.
DR AlphaFoldDB; A7RNY2; -.
DR STRING; 45351.A7RNY2; -.
DR EnsemblMetazoa; EDO46759; EDO46759; NEMVEDRAFT_v1g199903.
DR eggNOG; KOG1836; Eukaryota.
DR HOGENOM; CLU_320375_0_0_1; -.
DR InParanoid; A7RNY2; -.
DR PhylomeDB; A7RNY2; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0009887; P:animal organ morphogenesis; IBA:GO_Central.
DR GO; GO:0009888; P:tissue development; IBA:GO_Central.
DR CDD; cd00055; EGF_Lam; 3.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 4.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR008211; Laminin_N.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR10574:SF444; -; 1.
DR PANTHER; PTHR10574; NETRIN/LAMININ-RELATED; 1.
DR Pfam; PF00053; Laminin_EGF; 4.
DR Pfam; PF13385; Laminin_G_3; 1.
DR Pfam; PF00055; Laminin_N; 1.
DR PRINTS; PR00011; EGFLAMININ.
DR SMART; SM00180; EGF_Lam; 5.
DR SMART; SM00136; LamNT; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR PROSITE; PS01248; EGF_LAM_1; 2.
DR PROSITE; PS50027; EGF_LAM_2; 2.
DR PROSITE; PS51117; LAMININ_NTER; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00460};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292,
KW ECO:0000256|PROSITE-ProRule:PRU00460}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 759..784
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 242..468
FT /note="Laminin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51117"
FT DOMAIN 652..708
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 709..754
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT REGION 831..864
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 841..864
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 681..690
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 709..721
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 729..738
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
SQ SEQUENCE 906 AA; 99997 MW; 7317AB61D3664A97 CRC64;
MVRSIMLRKM IGENERLTIK SKVELSRLPP PRDNLVPHIQ RVNHRVASYK RADQAVFWRP
NPFEPGQGWE RNDDGLLEPV WSCGPVLPTS LIDIVESTVG EEEDDEEDGP INFDEAFSDE
DETLFVKAES ASPYKVIFQI EIQNYKLWFH YQTSASNVSV VELTPLQSQS KDLKEFQWHV
ISVSVVNTDL SYYIDGTFIQ GATLTGPIVD GGGLPRVGQT HSGGSQFEGF MQDIFMYDLA
ISNREIMEAL TGNLEKAYIA TNCRCPPGYP KISTSKPAKC AKNIENAEDE VFRLATTAHP
SEYMTDADTT TYWQSAVTDN ATVEVDLLYQ ELQIFFVIMV FYGPPPEAIL IERSRDRGST
YEPWQYFASD CQSSFGMENN GNLVNPDSIN CIQYQRPLPY SSATIAFKLE RSIPARPFGA
PCSNLYCSTR FLDFIKASNV RIQLYNHTLI QNEKHRYFAL KRVLVTGRCE CHGHAQKVTF
IKGNSSSPGR CRCECDPSTF TQGEKCESCL PMYNNKAFLR GTNDDPYPCV KCECNNHATA
CYYNSSLDPS PASRTVGGGG VCINCLHNTA GQFCHVCRDD FFREPGKSLS AVDVCSPCQC
TGPGVETGKT SCARVSSGNC TCKKYVREPT CGQCMKGYFN LSSSNPEGCQ ACNCNPKGTL
GGDRTPAGEL ECSGSNGKCA CLTNVQGLRC DKCVSAYYWN PSGYGCSPCN CDASGSLATN
CNSTGYCQCK PNIGGRRCDR CMPGSYGSPG SCKPCNCNVA GVGAGLGVFL AVAIVIIVIL
LCFLKRRPPS PPPEPVRKPK SLDPSLQSLD LRTQSLNVSY QGLVFKNKDT DGAVGASSSH
SYDEHRMDPL GKESGGDGEP GEEKQNDLLY ENTEFQQVLQ YLFRILDVQA AGFLNIFSLN
YFFRIF
//
