ID A7RRW9_NEMVE Unreviewed; 1001 AA.
AC A7RRW9;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EDO45835.1};
GN ORFNames=NEMVEDRAFT_v1g91061 {ECO:0000313|EMBL:EDO45835.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO45835.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO45835.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; DS469532; EDO45835.1; -; Genomic_DNA.
DR RefSeq; XP_001637898.1; XM_001637848.1.
DR AlphaFoldDB; A7RRW9; -.
DR STRING; 45351.A7RRW9; -.
DR EnsemblMetazoa; EDO45835; EDO45835; NEMVEDRAFT_v1g91061.
DR eggNOG; KOG0164; Eukaryota.
DR HOGENOM; CLU_000192_7_7_1; -.
DR InParanoid; A7RRW9; -.
DR OMA; VVFFKCL; -.
DR PhylomeDB; A7RRW9; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0015629; C:actin cytoskeleton; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005902; C:microvillus; IBA:GO_Central.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0031982; C:vesicle; IBA:GO_Central.
DR GO; GO:0051015; F:actin filament binding; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000146; F:microfilament motor activity; IBA:GO_Central.
DR GO; GO:0007015; P:actin filament organization; IBA:GO_Central.
DR GO; GO:0030050; P:vesicle transport along actin filament; IBA:GO_Central.
DR CDD; cd01378; MYSc_Myo1; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR010926; Myosin_TH1.
DR InterPro; IPR036072; MYSc_Myo1.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF713; UNCONVENTIONAL MYOSIN ID; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF06017; Myosin_TH1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51757; TH1; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000001593}.
FT DOMAIN 9..697
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 814..997
FT /note="TH1"
FT /evidence="ECO:0000259|PROSITE:PS51757"
FT REGION 575..597
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT BINDING 102..109
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1001 AA; 115834 MW; 9298E09689463A5B CRC64;
MAEQESLEYG KGDFVLLDEV TKTAFMENLE SRFHKERIYT YIGEVVVSVN PYKTLDIYGD
DKIQEYKMRE MYERPPHIFA LADASYRAMK RRSEDTCIMI SGESGSGKTE ASKIIMRYIA
AITNLSKQKE IERVKDILLK SNAILESFGN ARTNRNDNSS RFGKYMDIDF DFKGDPIGGH
IFNYLLEKSR VVKQQEGERN FHSFYQVPSD SMIGEYGLER DAMLYYYTKQ GKVPKISTIN
DSSLYKLNCD AMKSVGFSAE EQKTVWKLVA AILHLGNVVF THEDHEQAVV ENKDVLQIIA
KLLGLSHEML ERALCYRVVA ARGEVMEKGH NEKEAYHGRD ALAKAAYDRL FSWIVSRIND
SIEVRDKKEH GKCTVIGVLD IYGFEIFETN SFEQLCINYC NEKLQQLFIE LVLKEEQEEY
QREGIEWKSI HRCSQVEYFN NKIICDLIEQ SHKGIIAIMD EGCLNVGKVT DQMLLQTMDK
KLAKHPHYRS RLTDPSDKSM EFHRDFCIKH YAGNVIYSVE EFLDKNKDTL FQDFKRLLYN
SKHKSLKDMW PEGQESITKT TQRPATAGTL FKNSMIALVE KLISKRPFYV RCIKPNEIKS
PVAFDEKVVG NQVDYLGLLE NVRVRRAGYA FRMHYKRFLL RYKMTDAKTW PSYPGQDIDG
VREIVDSHGF SDDVKYGTTK IFIRTPQTIF ELEKSRAAKL PDLVFMLQRC WRGGIARMRA
KRMRSIYCIM TCFKRHQLRS FLSQIETRFK DCAQRSDFGK SNEWPESPKV AREFCDYLKA
IYGRWWALKV INRIPEEDKP ELALKSAAYN CLDGRRKHWG LRTRWMGDYL ALSDENPETE
LYKRCVHTKA GTVIFSSRVQ KINKHSKEES RTLVLTENAI LKMDSKYKVL KTIPLDKITS
LTVSAGQDQL IIVHIPHNDL VVCLLNNKKA NRVVEFMASI YKQVLQTQKK ALPVEVTANP
NCVLGNKAKR LTIEETDKAD HVTFKKQGGD GFVLVSPKIQ V
//
