ID A7RTK6_NEMVE Unreviewed; 2187 AA.
AC A7RTK6;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EDO45284.1};
GN ORFNames=NEMVEDRAFT_v1g201955 {ECO:0000313|EMBL:EDO45284.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO45284.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO45284.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
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DR EMBL; DS469537; EDO45284.1; -; Genomic_DNA.
DR RefSeq; XP_001637347.1; XM_001637297.1.
DR EnsemblMetazoa; EDO45284; EDO45284; NEMVEDRAFT_v1g201955.
DR eggNOG; KOG0613; Eukaryota.
DR HOGENOM; CLU_231372_0_0_1; -.
DR InParanoid; A7RTK6; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 6.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR11973; CELL SURFACE GLYCOPROTEIN MUC18-RELATED; 1.
DR PANTHER; PTHR11973:SF24; IG-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13895; Ig_2; 3.
DR Pfam; PF13927; Ig_3; 3.
DR SMART; SM00060; FN3; 1.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 4.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 8.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS50835; IG_LIKE; 6.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 73..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1191..1214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1445..1469
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 422..503
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 508..588
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 653..733
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 824..902
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 909..988
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1661..1739
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1880..1976
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 143..246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 263..293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1256..1291
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1325..1374
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1959..1986
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2060..2109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2127..2162
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 164..226
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 229..246
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1277..1291
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1334..1357
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2060..2093
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2187 AA; 237589 MW; D7D66F7F52658186 CRC64;
MRARPLAGAS RDWVTSSGVS SPASLSCVLD DLEPDTLYEV EVTVSVRGDT RRDTVYIRTT
PTAVEVNDQN STIVGLAVLV AILFLVIFSL IVYIVVLKRA GLTTRKKRPE ADNPGYSGFQ
NVAMQENANQ DKHTIPEMGD YEVAPLENRG PTPDPVPQYE SVNNAPVRPP NRSNVTQYDD
VTQGGNVTQY EATNNPSRDQ HVSANRQYDS ADSTRMSRQN PLARRARNGT GDQGERGYEN
TRKRGLPHEV YQSLQATTQH SENTQYAPLH PGTRIAARPG VRDEKGVGSD IRGNASSATT
WQWQYSTSVC FNDGENATLT WRVTLNSGEE VGAVNIWQQP VAGGPLSQMY SSTSGKTLAF
SDRVMWLSYS GSSPVYDVVF TLKVNNSADG FGTKQIQCRV NSKNYLIGQP ASDTILKVQD
KPENTIMVAN ASSVCIGGMA LLNCSAAGKP NNISYTLYRN GTEFASQMHG LFVLPLNTPG
VTIFTCVPSN EAGGGHNKSV TVTVKAPPRI TSLTPSQTVV EGNSFTMQCD ASGTAPLNIA
VSHPNGSVLT NSGSYTFSPI TRRDEGTYTC TVNNGNECSN GTNTTSITIN SAGKPENISY
TLYRNGTEFA SQMHGLFVLP RNLSGVSIFT CVPSNEAGDG HNKSVTVTVK EPPKITGFTP
PQTVVEGSNF TIWCNVSGTA PLKIAVSHPN GSVLTNSGSY TFSHITRRDE GTYTCTVNNG
NECSNDTNTT NITVNYKPEN TKLIPNEHIG CVRDVVSLNC SALANPDNIN YTLYRNDTAL
ASNMNGKFII SLNASGLSIF KCVPSNEVGD GENKTGFFTV KEPPRITRFT STQTEVEGSD
VTIRCNASGT EPLGVAIFHP NSSVLTNTGS YTFSPITRRD GGTYTCTVNN GNECPVDTKA
MNITVNYKPE KTSLTRLESS YCLGTSVYFN CTATGKPDDI HYSLFVNKTL LIEKSRGVFN
LTLNTLGKHE YTCVPNNTAG IGQNSTISID VQDASLNKPN AICLANDALT NVTVEMKTNI
LQPPVVTCTT GRASLISFSA DNKNPSYAVP LKRGQTISCS VEGYPLANIT FYLDIRRTNL
IMSWRIRNKN AIQKYGKWDV TDNDRQQIEN LEYFKSELLK NAPNYGLDID PNSVQPLAAI
PSNNVPLPLT TQAAPTTAAT PTTAATTKPG KCLTGVIIGT AVEVNDQNST IVGLAVLVAI
LFLVIICLIV YIAVLKRAGL TAKRERSEPD NPGYSGFQNV AMQENVNQDQ HVIPGVGDYE
VAPSDNRGPT PDPIPQYEPV NNTQTQPPNR RNVTQYEDVT QGSNVTQYED VTQEGNVTQY
EAMNRHASRD QHVPANRQYD SVDSTRMSRQ NPPARRARND TGDQGEPGYA NTRIRGLPPE
VYQSLQATTQ YSENAQYAPL HPGTRIAARP GGRDERGVGT DIRGILAEQK EDTLLKERSS
SMGSIHLVFL VGALLCLIIT STDASLTTWQ WQYNTSVCFD DGENATLTWR VTLNSGEEIG
AVSIWQQHVK AGGSPVQMYG TISGKEPAFS DRVMSLSYSG SSPVYDVVFT LKVNNSKDGF
GTIQLQCQSA GQTKNTRLYP LASSYCRGST ISFNCSATGN PRVIQYSLYL NNRHSSSRMD
GVFKDILLDT LGEQLFTCIP NNTVVAGQNT TATTIVQEFY SSVSIAPART ITTSEGSYVQ
MTCSASAVDL SSINWIKDSV PQGKGPKLTF PSISRDQGGV YNCTVIEGCG SASTDIAVYF
VDMERYSLKC ITSPAVIITI ETNKTPPPDM ICVTEGKTLL SKLTNKTGRK VTYEVELASL
DEAEVTCHAE GFTGSRQQFT VVAAASGQKR NGSFRINNGK HPPSDQMKTS IEKLNGLLQN
APRYNLTIEP TSVKMQQVKT PQLPKFDDVN PTHQRIKVTW SRPYSNAQCT MRARPLAGAS
RDWVTSSGFS NPASLSCVLD DLEPDTLYEV EVTLSVRETR GVTRSTSGPP PQLSRSGADN
PGFSGFQNVA MQENANQNQH TIPGMVDYEV APSEIRGPTP DPIPQYESVN NAPATTNRSN
VTQYEDVTQR GNVTQYEAMN SLPSRDQHVP ANRQYDSVDS TRMSGQNPPA RKARNDTGAQ
GETGYVNTSK RGLPHEVYQS LQATTQHSEN AQYAPLRPGT RIAARPGGRN ERGVSSALKE
SPYQGLNRMT ARDPFNQRVG TAHITNA
//
