ID A7RZI8_NEMVE Unreviewed; 476 AA.
AC A7RZI8;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 24-JAN-2024, entry version 73.
DE RecName: Full=RRM domain-containing protein {ECO:0000259|PROSITE:PS50102};
GN ORFNames=NEMVEDRAFT_v1g234681 {ECO:0000313|EMBL:EDO43102.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO43102.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO43102.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; DS469557; EDO43102.1; -; Genomic_DNA.
DR RefSeq; XP_001635165.1; XM_001635115.1.
DR AlphaFoldDB; A7RZI8; -.
DR STRING; 45351.A7RZI8; -.
DR EnsemblMetazoa; EDO43102; EDO43102; NEMVEDRAFT_v1g234681.
DR GeneID; 5515017; -.
DR KEGG; nve:5515017; -.
DR eggNOG; KOG4206; Eukaryota.
DR HOGENOM; CLU_039888_2_1_1; -.
DR InParanoid; A7RZI8; -.
DR OMA; CPFGPIT; -.
DR OrthoDB; 1331467at2759; -.
DR PhylomeDB; A7RZI8; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0005689; C:U12-type spliceosomal complex; IBA:GO_Central.
DR GO; GO:0097157; F:pre-mRNA intronic binding; IBA:GO_Central.
DR GO; GO:0030626; F:U12 snRNA binding; IBA:GO_Central.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR CDD; cd12238; RRM1_RBM40_like; 1.
DR CDD; cd12239; RRM2_RBM40_like; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 6.10.250.610; -; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR034147; RBM40_RRM1.
DR InterPro; IPR045164; RBM41/RNPC3.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR16105:SF0; RRM DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR16105; UNCHARACTERIZED; 1.
DR Pfam; PF00076; RRM_1; 2.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50102; RRM; 2.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 10..85
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 386..469
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 88..133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 200..285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 304..348
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 100..127
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 245..275
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 306..328
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 476 AA; 53528 MW; 75C59A1BFAE2758E CRC64;
MAADSRKDYC KLFVRHLPNV LSNADKEDFF KHFGARSVIC MGRSGKMRDT AFVEFPDDTT
ASKALRRLHQ LEILGSALVV EYATKQQEQT AAQHSNRMSP KKEAASENSK DQQDVTSEMD
KQNRIEHGIA PKLGLKYPGN PHLTYLYPPP TASILTNIAH TLACVPKFYT QVLHLMNKMN
LPAPFGEVTP TPPIVGATVA PPSNAVPDED VYLSSEESEI ESDEEEKERR LKEQSMFGMQ
AKPKQDHATA RKRTKLQPAK VPEPKKRKAP PKESQPFEEA FETSQVPQRK IAFNLTDAIT
SIFEAGPPFS DTQGTPGDSQ QGSEGFGVFA PSQKQPEEKE EGEVDEPLLE TNEFVSSREL
KANRMSEKEI KAMSQFKNYS PGDPTSRLYV KNLSRQVEDK DLMYVFGRYV DFSVGEQKDR
FDIRLMKEGR MKGQAFVTLP SEEKAKRALR EVHGYMLHGK PIVIQFARSA KAKEAK
//
