ID A7S6G2_NEMVE Unreviewed; 663 AA.
AC A7S6G2;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EDO40715.1};
GN ORFNames=NEMVEDRAFT_v1g106355 {ECO:0000313|EMBL:EDO40715.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO40715.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO40715.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
CC -!- SIMILARITY: Belongs to the peptidase M28 family. M28B subfamily.
CC {ECO:0000256|ARBA:ARBA00005634}.
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DR EMBL; DS469587; EDO40715.1; -; Genomic_DNA.
DR RefSeq; XP_001632778.1; XM_001632728.1.
DR AlphaFoldDB; A7S6G2; -.
DR EnsemblMetazoa; EDO40715; EDO40715; NEMVEDRAFT_v1g106355.
DR eggNOG; KOG2195; Eukaryota.
DR HOGENOM; CLU_005688_3_2_1; -.
DR InParanoid; A7S6G2; -.
DR OMA; YPRKDGR; -.
DR PhylomeDB; A7S6G2; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0004180; F:carboxypeptidase activity; IBA:GO_Central.
DR CDD; cd08022; M28_PSMA_like; 1.
DR CDD; cd02121; PA_GCPII_like; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 1.20.930.40; Transferrin receptor-like, dimerisation domain; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR007484; Peptidase_M28.
DR InterPro; IPR039373; Peptidase_M28B.
DR InterPro; IPR007365; TFR-like_dimer_dom.
DR InterPro; IPR036757; TFR-like_dimer_dom_sf.
DR PANTHER; PTHR10404:SF46; GLUTAMATE CARBOXYPEPTIDASE 2 HOMOLOG; 1.
DR PANTHER; PTHR10404; N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF04389; Peptidase_M28; 1.
DR Pfam; PF04253; TFR_dimer; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF47672; Transferrin receptor-like dimerisation domain; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001593}.
FT DOMAIN 96..181
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 279..477
FT /note="Peptidase M28"
FT /evidence="ECO:0000259|Pfam:PF04389"
FT DOMAIN 542..655
FT /note="Transferrin receptor-like dimerisation"
FT /evidence="ECO:0000259|Pfam:PF04253"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EDO40715.1"
SQ SEQUENCE 663 AA; 74857 MW; 367367AB81EFE07E CRC64;
NILDSSRNFT KRPHIGGGEQ SQKLGCYIRD KWLSYGFDKV EMPRYDVLLS LPSRDKPNAV
KIIDNSTGEV LTDEPSENDP LVLPPFLAYS PPGDVMGELI YVNYGTVEDF KKFEDLKQSC
KGKIAIMRYG RIFRGDKVKH AAECGAIGVI LFSDPIDVAP EGMDKTFPKT WWLSGTGAQR
GSILKNNYYG DPLTPLLPST EGIYRNSRND TNALPTIPAQ PLPYNDALEF LKRMKGPEAP
DSWQGGLQIK YKLGPGFTDP NTTTRLIVNN EFVTRPGYNV IGTITGQEEP DRIVLYGNHR
DAWVFGGVDS SSGSAVMMEL SRGLGYLLKN KKWRPRRTIM LCSWAVEEYG LIGSAEWVNE
NEKMLTDRAV AYINIDSGVA GNYSFNAAGN PLLQEMAFNE TRLVRDYNTR SMSVYDKWSM
SYPSDDHAIP AFKTLGSGSD YTTFVQSVGI PSLDMSYTFK DSRAWPYPVY HSVHDTFYLQ
KKFNDPYFKS HLTMAKISGK LLTAVADSPL LPFSTRSYKD SLAKGYRQLQ KTFQDRLSAQ
NITLDYIGKE IENFADASDN FESAKATLDN TTDFMKLRLL NDQMAKLERA FIWPYGLPGR
PDTRHVLYAP QRHNLYGSAV FPGIYDAMYD VRDDWMEVKN QISIVTQALR SAVQFIQPIQ
RQE
//
