ID A7S8J2_NEMVE Unreviewed; 418 AA.
AC A7S8J2;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=Fibronectin type-III domain-containing protein {ECO:0000259|PROSITE:PS50853};
GN ORFNames=NEMVEDRAFT_v1g108749 {ECO:0000313|EMBL:EDO39996.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO39996.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO39996.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
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DR EMBL; DS469598; EDO39996.1; -; Genomic_DNA.
DR RefSeq; XP_001632059.1; XM_001632009.1.
DR AlphaFoldDB; A7S8J2; -.
DR STRING; 45351.A7S8J2; -.
DR EnsemblMetazoa; EDO39996; EDO39996; NEMVEDRAFT_v1g108749.
DR eggNOG; KOG4228; Eukaryota.
DR HOGENOM; CLU_629388_0_0_1; -.
DR InParanoid; A7S8J2; -.
DR OMA; TERAQNG; -.
DR PhylomeDB; A7S8J2; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR GO; GO:0043235; C:receptor complex; IBA:GO_Central.
DR GO; GO:0019955; F:cytokine binding; IBA:GO_Central.
DR GO; GO:0004896; F:cytokine receptor activity; IBA:GO_Central.
DR GO; GO:0019221; P:cytokine-mediated signaling pathway; IBA:GO_Central.
DR CDD; cd00063; FN3; 4.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR23036; CYTOKINE RECEPTOR; 1.
DR PANTHER; PTHR23036:SF151; MYOTACTIN FORM B; 1.
DR Pfam; PF00041; fn3; 4.
DR SMART; SM00060; FN3; 4.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR PROSITE; PS50853; FN3; 4.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 37..136
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 141..229
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 230..324
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 329..418
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EDO39996.1"
SQ SEQUENCE 418 AA; 44943 MW; 34A113D35B4A6E59 CRC64;
MYDVRVTRPT YHIALLGVGI VTIAVTVKTL ESLPSAPPSN LRVLNQTSTS IEIAWDGIPV
ERMHGVLLGY RVAYGLLGIP GSNASLVQID VAEPDTYQQT LTGLRKYSSY WITVTGFTSI
GDGPVSEPVN ATTDQHVPSS PPSNVRANVN GSTSIQVDWD KVPSPLVHGI LMGYLVTYRK
SGTGVMAENE TAPGTTSILL TGLQPYFLYD IQVSAFTVKG CGPQSVPSVA PTIIKAANQS
STSLTVQWSR IPPGLTRGVL LGYRVTYTQY DSGATYTRDT AAGVTRMTLT SLTPYMVYTV
SVAGFTSKGT GPESYNITLS TDEDVPIASP IHVQAANQSS TSLRVRWGPV PGGRVHDVLL
GYHVTYRQVN GSWFRSDVTK ERELVLSGLQ VYTVYSVRVA AYTRMGDGPA SPEVIART
//
