ID A7S9D1_NEMVE Unreviewed; 491 AA.
AC A7S9D1;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 24-JAN-2024, entry version 66.
DE RecName: Full=SH3 domain-containing protein {ECO:0000259|PROSITE:PS50002};
GN ORFNames=NEMVEDRAFT_v1g243726 {ECO:0000313|EMBL:EDO39651.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO39651.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO39651.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
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DR EMBL; DS469603; EDO39651.1; -; Genomic_DNA.
DR RefSeq; XP_001631714.1; XM_001631664.1.
DR AlphaFoldDB; A7S9D1; -.
DR STRING; 45351.A7S9D1; -.
DR EnsemblMetazoa; EDO39651; EDO39651; NEMVEDRAFT_v1g243726.
DR GeneID; 5511294; -.
DR KEGG; nve:5511294; -.
DR eggNOG; ENOG502RTT2; Eukaryota.
DR HOGENOM; CLU_039664_1_0_1; -.
DR InParanoid; A7S9D1; -.
DR OrthoDB; 2875265at2759; -.
DR PhylomeDB; A7S9D1; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0005929; C:cilium; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0090251; P:protein localization involved in establishment of planar polarity; IBA:GO_Central.
DR CDD; cd00174; SH3; 3.
DR Gene3D; 2.30.30.40; SH3 Domains; 3.
DR InterPro; IPR039687; NPHP1.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR15176; NEPHROCYSTIN; 1.
DR PANTHER; PTHR15176:SF1; NEPHROCYSTIN-1; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF07653; SH3_2; 1.
DR SMART; SM00326; SH3; 3.
DR SUPFAM; SSF50044; SH3-domain; 3.
DR PROSITE; PS50002; SH3; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 85..144
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 202..262
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 425..488
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 21..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 150..170
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 176..195
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 269..373
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 394..419
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 154..170
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 491 AA; 55030 MW; 1964498D29133B71 CRC64;
MAFLCPSQLT VKKKVLQGKA PYPDTYQLNG DSSPGVEHKS ALKSPRSSTD SSHKSNHRTV
RIDEAALNKE SKVERKIRTA TYDRPANIRV KAAHDYSSED PEELNLSKGQ TVKILYQQHD
WLYVVDLFGN EGFIPFSYCS DFNNSIDSKS STSGFTDSHE ESDEIEKAAE RRKIDRFSKH
RNDKHKHNSK QKTPVVYFPK RPYGPKLTVL FNYKARYEND VSVERGEYVM LLNDQDADWL
WVATEDGEEG FIPRTFVISH ACEGCRRRLS QEPSSSSSFN RKNISPLGNG SVSALTKDTS
LHKVTTDNTS SNSDKQSEKC NVNGHTRNSR NSTPHGSKMN LHSSQTELNP VYNSSPTLTE
ITPSSPELTP ISSELAPSLD HSLLNGDIYS SDITPTSSSS ADVEPKSRNL SDATSSASSD
KKLELKGSRL ISLYEYEGSA FDDLTVHAGE YVYANLKDQI VPKWIWAYSP YRKRSGFIPE
AYLKEPVVTD I
//
