ID   A7SC07_NEMVE            Unreviewed;       862 AA.
AC   A7SC07;
DT   02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT   02-OCT-2007, sequence version 1.
DT   27-MAR-2024, entry version 60.
DE   RecName: Full=Ig-like domain-containing protein {ECO:0000259|PROSITE:PS50835};
GN   ORFNames=NEMVEDRAFT_v1g209947 {ECO:0000313|EMBL:EDO38723.1};
OS   Nematostella vectensis (Starlet sea anemone).
OC   Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC   Edwardsiidae; Nematostella.
OX   NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO38723.1, ECO:0000313|Proteomes:UP000001593};
RN   [1] {ECO:0000313|EMBL:EDO38723.1, ECO:0000313|Proteomes:UP000001593}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX   PubMed=17615350; DOI=10.1126/science.1139158;
RA   Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA   Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA   Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA   Technau U., Martindale M.Q., Rokhsar D.S.;
RT   "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT   genomic organization.";
RL   Science 317:86-94(2007).
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DR   EMBL; DS469620; EDO38723.1; -; Genomic_DNA.
DR   RefSeq; XP_001630786.1; XM_001630736.1.
DR   AlphaFoldDB; A7SC07; -.
DR   EnsemblMetazoa; EDO38723; EDO38723; NEMVEDRAFT_v1g209947.
DR   KEGG; nve:5510331; -.
DR   eggNOG; KOG2408; Eukaryota.
DR   eggNOG; KOG3544; Eukaryota.
DR   HOGENOM; CLU_332125_0_0_1; -.
DR   InParanoid; A7SC07; -.
DR   OrthoDB; 2919767at2759; -.
DR   PhylomeDB; A7SC07; -.
DR   Proteomes; UP000001593; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR   InterPro; IPR008160; Collagen.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR013098; Ig_I-set.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   PANTHER; PTHR12231; CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN; 1.
DR   PANTHER; PTHR12231:SF253; NEURAL CELL ADHESION MOLECULE; 1.
DR   Pfam; PF01391; Collagen; 2.
DR   Pfam; PF07679; I-set; 1.
DR   Pfam; PF13927; Ig_3; 2.
DR   SMART; SM00409; IG; 3.
DR   SMART; SM00408; IGc2; 3.
DR   SUPFAM; SSF48726; Immunoglobulin; 3.
DR   PROSITE; PS50835; IG_LIKE; 3.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          209..296
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          299..385
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          388..471
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   REGION          75..97
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          126..208
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          581..618
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        183..197
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   862 AA;  93398 MW;  6EB69FB1769070AB CRC64;
     MDGKTTTGIA TVFLILAILL YEDLMTRRFR GLEDRIGRLE STVSDLQLLQ RRNGRFFSDI
     NTRVLSNLIM LRIQRPRNSQ SHRRQRRSPS NESNSTISLA TSLAEEIAKH LSPAVIRLCM
     GGSLTCPPGP RGPPGRPGHP GQKGTRGRRG QRGRRGNPGS PGPKGTPGKD GRRGAVGSKG
     MKGQKGEKGE RGIGVRGEKG APGDTLSAPN AIVSPALITI NASDTAVFHC AASGVPKPVL
     IWSKVDGAPL MESSYKMLGN GRLVLENTTL EDAGLYECKA INLLGESSAT MRLVVTVPPS
     VSIDIGPTYV QEGDNVMLPK CHVTGFPLPE INWTRSAGQL PRRRVMTSGG QLSILAARAN
     DSGDYFCSAR NHIGSTIART QLVVFALPRF IISPPKSLKA EVGSDVILPC KAYGSPPPLV
     ITWHRHGKSI PQERSGVIDG VLRLIDVTTA DSGVYVCTAT SSGIFDAQAM TRLEVLENTA
     ASANAAPAKQ DGRSLTNSTH AKLDMKNGFE GKVSEKGKMT LKLDDKTSSK NGRPLNILSG
     NSTWKRNNAS VMSEINKPAP VENQGSNIEI GKLVTPTRNL SGMPMSRSPN YGNNANVKDN
     LKQKSNNTSA GDPENGKSVK ITESTKIMEK GDISALEKLM RRKEGIEKPT KSTKISNITE
     IPVKKDRVLG KIRATEKPDN GKIEMRYVYK PTNSRNRGEI PITAKAENGK AVNGKSVEPT
     KKMTKKPVKQ KVEKRKMGIE RMETGKRNAE FDKRKDKISA KKSVGLLNIA FPIKKQENKK
     SGNLSGIVIG HGYLKSKSIK SGKPGMMKML PTKKRKGYKG GVGKLDRFSN LGGVRKIDST
     VNPLIEEIEN YKGLEDFDKE SN
//