ID A7SKN6_NEMVE Unreviewed; 418 AA.
AC A7SKN6;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE RecName: Full=Histone deacetylase domain-containing protein {ECO:0000259|Pfam:PF00850};
GN ORFNames=NEMVEDRAFT_v1g190860 {ECO:0000313|EMBL:EDO35756.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO35756.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO35756.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
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DR EMBL; DS469689; EDO35756.1; -; Genomic_DNA.
DR RefSeq; XP_001647545.1; XM_001647495.1.
DR AlphaFoldDB; A7SKN6; -.
DR STRING; 45351.A7SKN6; -.
DR EnsemblMetazoa; EDO35756; EDO35756; NEMVEDRAFT_v1g190860.
DR KEGG; nve:5525263; -.
DR eggNOG; KOG1343; Eukaryota.
DR HOGENOM; CLU_007727_8_5_1; -.
DR InParanoid; A7SKN6; -.
DR OMA; NIALNEC; -.
DR OrthoDB; 124800at2759; -.
DR PhylomeDB; A7SKN6; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0004407; F:histone deacetylase activity; IEA:UniProtKB-EC.
DR CDD; cd11681; HDAC_classIIa; 1.
DR Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR InterPro; IPR000286; His_deacetylse.
DR InterPro; IPR023801; His_deacetylse_dom.
DR InterPro; IPR037138; His_deacetylse_dom_sf.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR PANTHER; PTHR10625:SF15; HISTONE DEACETYLASE; 1.
DR PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR Pfam; PF00850; Hist_deacetyl; 1.
DR PRINTS; PR01270; HDASUPER.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001593}.
FT DOMAIN 14..329
FT /note="Histone deacetylase"
FT /evidence="ECO:0000259|Pfam:PF00850"
SQ SEQUENCE 418 AA; 45214 MW; 245031C4045B12F0 CRC64;
MLKHQCSCGD ATSHPEHPGR LQSIWARLQE TGVVNMCDRV RPRKATLAEI LSVHSEQHTM
LFGGSTQCRT KAEDGTITTL KCFSSLPCGG MGVDGDTIWN EVHSANAARM AVGCVVELTQ
KVAAQEIKNG MAIVRPPGHH AEAHQAMGFC YFNNVAIAAR LLRLKMSIDR VLIVDWDIHH
GNGTQQMFYD DPHVLYISLH RHDDGTFFPG TGKAEECGAG IGVGYNVNIA WSGGLDPPYG
DAEYLAAFRS VVIPIAKEFQ PDIILVSCGF DAAAGHSPQL GGYKVSAPCF AHLTNQLMDL
ADGRVVLALE GGYSLPSLCD AAEACLRALL SDTLPEIPKE SLKRAPNPNA IAVLEKTIAI
QSRYWSSVKR SINHISHSVV EAQQREKEEA ETVSALASLS MGVVQDSKVA DVQMEDDS
//
