ID A7SNL5_NEMVE Unreviewed; 407 AA.
AC A7SNL5;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 24-JAN-2024, entry version 60.
DE RecName: Full=Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein {ECO:0000259|SMART:SM00014};
GN ORFNames=NEMVEDRAFT_v1g215007 {ECO:0000313|EMBL:EDO34697.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO34697.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO34697.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
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DR EMBL; DS469722; EDO34697.1; -; Genomic_DNA.
DR RefSeq; XP_001626797.1; XM_001626747.1.
DR AlphaFoldDB; A7SNL5; -.
DR STRING; 45351.A7SNL5; -.
DR EnsemblMetazoa; EDO34697; EDO34697; NEMVEDRAFT_v1g215007.
DR eggNOG; KOG2822; Eukaryota.
DR HOGENOM; CLU_043042_1_0_1; -.
DR InParanoid; A7SNL5; -.
DR PhylomeDB; A7SNL5; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IBA:GO_Central.
DR GO; GO:0042392; F:sphingosine-1-phosphate phosphatase activity; IBA:GO_Central.
DR GO; GO:0046839; P:phospholipid dephosphorylation; IBA:GO_Central.
DR GO; GO:0006670; P:sphingosine metabolic process; IBA:GO_Central.
DR Gene3D; 1.20.144.10; Phosphatidic acid phosphatase type 2/haloperoxidase; 1.
DR InterPro; IPR036938; P_Acid_Pase_2/haloperoxi_sf.
DR InterPro; IPR000326; P_Acid_Pase_2/haloperoxidase.
DR PANTHER; PTHR14969:SF39; ACIDPPC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR14969; SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE; 1.
DR Pfam; PF01569; PAP2; 1.
DR SMART; SM00014; acidPPc; 1.
DR SUPFAM; SSF48317; Acid phosphatase/Vanadium-dependent haloperoxidase; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 104..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..164
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..220
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 232..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 102..220
FT /note="Phosphatidic acid phosphatase type 2/haloperoxidase"
FT /evidence="ECO:0000259|SMART:SM00014"
SQ SEQUENCE 407 AA; 46175 MW; 7D925CC1E3853E4A CRC64;
MATESESFCQ TDDESCEKLS DSEEELEECI VAPIDKLGVV GRWMRHRLLG SILMGTPPLV
AIQRRRSPFR TTIMKINSFF GTEEFYTPLV CLMTWVIDAK LGRLICFLMG IGFYVAGFVK
NLLCLPRPSN PPIVPLEPSS FETWGLPSHH AVLGVLIPWY IWLYSLLHFN FSQWQFITLF
AVIVLWSVSV MFSRLYLGVH SPADIVVGGI IGCIILSIWV RADNFLDRSI SFGNNVIPQV
IIYSIILLAV HPRPEAETNS FFETVCMTGV TVGFAIGRST IAKHSSIFKA VMESADGYAL
VMITRAICKE VFMFLISLAY RVVDIEYFSG RKITNYYFHT AYSSSFKLPP VEDQKSKRKI
RKVKSRSENI RTKWNIDYPV RFLTYACMGW MCICGNPLLC HSLGLTL
//
