ID A7TRK0_VANPO Unreviewed; 442 AA.
AC A7TRK0;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 24-JAN-2024, entry version 64.
DE RecName: Full=Magnesium transporter {ECO:0000256|RuleBase:RU366042};
GN ORFNames=Kpol_1071p5 {ECO:0000313|EMBL:EDO15098.1};
OS Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX NCBI_TaxID=436907 {ECO:0000313|Proteomes:UP000000267};
RN [1] {ECO:0000313|EMBL:EDO15098.1, ECO:0000313|Proteomes:UP000000267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 /
RC NRRL Y-8283 / UCD 57-17 {ECO:0000313|Proteomes:UP000000267};
RX PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT species descended from a whole-genome duplication.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000256|RuleBase:RU366042}; Multi-pass membrane protein
CC {ECO:0000256|RuleBase:RU366042}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC family. {ECO:0000256|ARBA:ARBA00009765, ECO:0000256|RuleBase:RU366042}.
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DR EMBL; DS480481; EDO15098.1; -; Genomic_DNA.
DR RefSeq; XP_001642956.1; XM_001642906.1.
DR AlphaFoldDB; A7TRK0; -.
DR GeneID; 5543151; -.
DR KEGG; vpo:Kpol_1071p5; -.
DR eggNOG; KOG2662; Eukaryota.
DR HOGENOM; CLU_025144_1_0_1; -.
DR InParanoid; A7TRK0; -.
DR OMA; MATMFLT; -.
DR OrthoDB; 73031at2759; -.
DR PhylomeDB; A7TRK0; -.
DR Proteomes; UP000000267; Unassembled WGS sequence.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR CDD; cd12823; Mrs2_Mfm1p-like; 1.
DR Gene3D; 2.40.128.330; -; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 1.
DR InterPro; IPR039204; MRS2-like.
DR PANTHER; PTHR13890:SF27; MAGNESIUM TRANSPORTER MRS2, MITOCHONDRIAL; 1.
DR PANTHER; PTHR13890; RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|RuleBase:RU366042};
KW Magnesium {ECO:0000256|RuleBase:RU366042};
KW Membrane {ECO:0000256|RuleBase:RU366042};
KW Mitochondrion {ECO:0000256|RuleBase:RU366042};
KW Mitochondrion inner membrane {ECO:0000256|RuleBase:RU366042};
KW Reference proteome {ECO:0000313|Proteomes:UP000000267};
KW Transmembrane {ECO:0000256|RuleBase:RU366042};
KW Transmembrane helix {ECO:0000256|RuleBase:RU366042};
KW Transport {ECO:0000256|RuleBase:RU366042}.
FT TRANSMEM 312..330
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366042"
FT TRANSMEM 342..363
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366042"
SQ SEQUENCE 442 AA; 50790 MW; CC75382D54FD660B CRC64;
MLKILHFKPL SHITQRRLLS VSSVKFQIKN KSLLPPLNSQ LLSLKPVTPN DSFVSCTVFN
GKGDVIAVSQ KFPKWSFLRQ YELYPRDLRK IDASSIDIIP TILVKKNCIV INMLYIKALI
SKDKLYVFDT TNQTAAMKLG VLMYDLESKL SSKNKQSFLN SNISQAYEHK ALESVLINIM
CALETELKIH SSICGEILTE LENEVNRDKL RDLLIKSKNL SLFYQKSLLI REVLDEILEN
DDDLAGLYLT DKKTEKDDFA ELEMLLETYY TQCDEFVQQS GSLLQDIKST EEIVNIMLDA
NRNSLMLLEL KVTIYTLGIT VATLIPAFYG MNLKNFIEES NLGFGGVVFF SFVIAIMVTR
TNFRSLRSVT RLSMLNNHSG SLSAKHRKLA KEYTAQEVPT LWSRFKMGFE CFLFGKNPGK
HLIHTKEKRE MVWKWLMEDE KK
//
