ID A7U0E5_LEULE Unreviewed; 365 AA.
AC A7U0E5;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=caffeate O-methyltransferase {ECO:0000256|ARBA:ARBA00039011};
DE EC=2.1.1.68 {ECO:0000256|ARBA:ARBA00039011};
OS Leucaena leucocephala (White popinac) (Leucaena glauca).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Caesalpinioideae; mimosoid clade;
OC Mimoseae; Leucaena.
OX NCBI_TaxID=3866 {ECO:0000313|EMBL:ABS57468.1};
RN [1] {ECO:0000313|EMBL:ABS57468.1}
RP NUCLEOTIDE SEQUENCE.
RA Dwivedi U.N.;
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABU41320.1}
RP NUCLEOTIDE SEQUENCE.
RA Dwivedi U.N.;
RT "Leucaena leucocephala caffeic acid o-methyl transferase genomic
RT sequence.";
RL Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Aromatic compound metabolism; phenylpropanoid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004928}.
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DR EMBL; EF546435; ABS57468.1; -; mRNA.
DR EMBL; EF611249; ABU41320.1; -; Genomic_DNA.
DR AlphaFoldDB; A7U0E5; -.
DR BRENDA; 2.1.1.68; 2996.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:UniProt.
DR GO; GO:0009809; P:lignin biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR012967; Plant_MeTrfase_dimerisation.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11746:SF199; FLAVONE 3'-O-METHYLTRANSFERASE 1; 1.
DR PANTHER; PTHR11746; O-METHYLTRANSFERASE; 1.
DR Pfam; PF08100; Dimerisation; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR PIRSF; PIRSF005739; O-mtase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 2: Evidence at transcript level;
KW Lignin biosynthesis {ECO:0000256|ARBA:ARBA00022733};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000313|EMBL:ABS57468.1}.
FT DOMAIN 34..85
FT /note="Plant methyltransferase dimerisation"
FT /evidence="ECO:0000259|Pfam:PF08100"
FT DOMAIN 140..345
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
FT ACT_SITE 269
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR005739-1"
SQ SEQUENCE 365 AA; 39839 MW; B9ACAB9D2EB81035 CRC64;
MGSTGETQII PTHVNDEEAN LFAMQLASAS VLPMILKSAL ELDLLEIIAK AGPNAQLSPS
NIAAQLPTKN PDAAVMLDRM MRLLACYNVL SCSVRTLPDG KIERLYGLAP VAKYLVKNED
GVSIAPLNLM NQDKVLMESW YYLKDAVLEG GIPFNKAHGM TSFEYHGKDL RFNKVFNKGM
ADHSTITMKK ILETYTGFEG LTSLVDVGGG TGAVISMIVS KYPSINGINF DLPHVIEDAP
SYPGVEHVGG DMFVSVPKAD AVFMKWICHD WSDEHCVKFL KNCYDALPEN GKVIVAECIL
PASPDSSLAT KGVVHIDVIM LAHNPGGKER TEKEFEALAK AAGFQGFRVC CSAFNTYIME
FLKKP
//
