ID A7VHI2_9CLOT Unreviewed; 248 AA.
AC A7VHI2;
DT 23-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 23-OCT-2007, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=Topoisomerase DNA-binding C4 zinc finger domain protein {ECO:0000313|EMBL:EDO56691.1};
GN ORFNames=CLOL250_02379 {ECO:0000313|EMBL:EDO56691.1};
OS Clostridium sp. L2-50.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=411489 {ECO:0000313|EMBL:EDO56691.1, ECO:0000313|Proteomes:UP000003352};
RN [1] {ECO:0000313|EMBL:EDO56691.1, ECO:0000313|Proteomes:UP000003352}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L2-50 {ECO:0000313|EMBL:EDO56691.1,
RC ECO:0000313|Proteomes:UP000003352};
RA Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA Gordon J.;
RT "Draft genome sequence of Clostridium sp. L2-50.";
RL Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EDO56691.1, ECO:0000313|Proteomes:UP000003352}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L2-50 {ECO:0000313|EMBL:EDO56691.1,
RC ECO:0000313|Proteomes:UP000003352};
RA Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA Thiruvilangam P., Bhonagiri V., Nash W.E., Hodges J., Shah N., Mardis E.R.,
RA Wilson R.K.;
RL Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDO56691.1}.
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DR EMBL; AAYW02000018; EDO56691.1; -; Genomic_DNA.
DR RefSeq; WP_008399833.1; NZ_DS480312.1.
DR AlphaFoldDB; A7VHI2; -.
DR eggNOG; COG0551; Bacteria.
DR HOGENOM; CLU_068011_2_0_9; -.
DR OrthoDB; 9813328at2; -.
DR Proteomes; UP000003352; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003916; F:DNA topoisomerase activity; IEA:InterPro.
DR GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR Gene3D; 3.30.65.10; Bacterial Topoisomerase I, domain 1; 1.
DR InterPro; IPR011528; NERD.
DR InterPro; IPR013498; Topo_IA_Znf.
DR Pfam; PF08378; NERD; 1.
DR Pfam; PF01396; zf-C4_Topoisom; 1.
DR SUPFAM; SSF57783; Zinc beta-ribbon; 1.
DR PROSITE; PS50965; NERD; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000313|EMBL:EDO56691.1};
KW Isomerase {ECO:0000313|EMBL:EDO56691.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..23
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 26..142
FT /note="NERD"
FT /evidence="ECO:0000259|PROSITE:PS50965"
SQ SEQUENCE 248 AA; 28358 MW; F84573D63942D5A3 CRC64;
MNWPIWVIIG FAVAGILVGW LQAKVKGIIG EKKVSVVLAT LPDSDYIILN DVMLPTEKGS
TQIDHIVVSL YGIFVIETKN YKGWITGSPY AEQWTKNMYG KKYKFYNPIR QNYGHIKNLS
TILGLSEEKF ISIVAFSANS TIKVKSRDYV VHILQVKKVI KSYKEPVFTQ DEIKQLADRI
KTINEASSDL RVGHVKRIKE AQNIRKNNKE VQRICPKCGG KIVYKRGKYG KFLGCTNYPN
CRYTKEMK
//
