ID A7VM92_9CICH Unreviewed; 274 AA.
AC A7VM92;
DT 23-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 23-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Long wavelength-sensitive opsin {ECO:0000313|EMBL:BAF76670.1};
DE Flags: Fragment;
GN Name=LWS {ECO:0000313|EMBL:BAF76670.1};
OS Haplochromis fischeri.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX NCBI_TaxID=1078953 {ECO:0000313|EMBL:BAF76670.1};
RN [1] {ECO:0000313|EMBL:BAF76670.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Fin {ECO:0000313|EMBL:BAF76670.1};
RX PubMed=17652334; DOI=10.1093/molbev/msm138;
RA Samonte I.E., Satta Y., Sato A., Tichy H., Takahata N., Klein J.;
RT "Gene flow between species of Lake Victoria haplochromine fishes.";
RL Mol. Biol. Evol. 24:2069-2080(2007).
CC -!- FUNCTION: Visual pigments are the light-absorbing molecules that
CC mediate vision. They consist of an apoprotein, opsin, covalently linked
CC to cis-retinal. {ECO:0000256|ARBA:ARBA00002881}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU004951}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU004951}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family. Opsin
CC subfamily. {ECO:0000256|RuleBase:RU004951}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU004951}.
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DR EMBL; AB326126; BAF76670.1; -; Genomic_DNA.
DR AlphaFoldDB; A7VM92; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW.
DR GO; GO:0007602; P:phototransduction; IEA:UniProtKB-KW.
DR GO; GO:0007601; P:visual perception; IEA:InterPro.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR001760; Opsin.
DR InterPro; IPR000378; Opsin_red/grn.
DR PANTHER; PTHR24240:SF17; MEDIUM-WAVE-SENSITIVE OPSIN 1-RELATED; 1.
DR PANTHER; PTHR24240; OPSIN; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00238; OPSIN.
DR PRINTS; PR00575; OPSINREDGRN.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Chromophore {ECO:0000256|RuleBase:RU004951};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040,
KW ECO:0000256|RuleBase:RU004951};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU004951};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Photoreceptor protein {ECO:0000256|RuleBase:RU004951};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU004951};
KW Retinal protein {ECO:0000256|RuleBase:RU004951};
KW Sensory transduction {ECO:0000256|RuleBase:RU004951};
KW Transducer {ECO:0000256|RuleBase:RU004951};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU004951};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU004951}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004951"
FT TRANSMEM 45..75
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004951"
FT TRANSMEM 81..101
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004951"
FT TRANSMEM 122..143
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004951"
FT TRANSMEM 173..203
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004951"
FT TRANSMEM 224..247
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004951"
FT DOMAIN 24..274
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:BAF76670.1"
FT NON_TER 274
FT /evidence="ECO:0000313|EMBL:BAF76670.1"
SQ SEQUENCE 274 AA; 30701 MW; 5B666C992631BF60 CRC64;
IAPRWIYNLA TLWMFVVVVL SVFTNGLVLV ATMKFKKLRH PLNWILVNLA IADLGETVFA
STISVCNQFF GYFILGHPMC IFEGYVVSVC GIAALWSLTI ISWERWIVVC KPFGNVKFDA
KWATAGIVFS WVWAAVWCAP PIFGWSRYWP HGLKTSCGPD VFSGSEDPGV QSYMIVLMLT
CCIFPLAIII LCYLAVWMAI RAVAMQQKES ESTQKAEREV SRMVVVMIVA YCVCWGPYTF
FACFAAANPG YAFHPLAADM PAYFAKSATI YNPI
//
