ID A7ZQL2_ECO24 Unreviewed; 286 AA.
AC A7ZQL2;
DT 23-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 23-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=Electron transfer flavoprotein {ECO:0000313|EMBL:ABV21073.1};
GN OrderedLocusNames=EcE24377A_3071 {ECO:0000313|EMBL:ABV21073.1};
OS Escherichia coli O139:H28 (strain E24377A / ETEC).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=331111 {ECO:0000313|EMBL:ABV21073.1, ECO:0000313|Proteomes:UP000001122};
RN [1] {ECO:0000313|Proteomes:UP000001122}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E24377A / ETEC {ECO:0000313|Proteomes:UP000001122};
RX PubMed=18676672; DOI=10.1128/JB.00619-08;
RA Rasko D.A., Rosovitz M.J., Myers G.S., Mongodin E.F., Fricke W.F.,
RA Gajer P., Crabtree J., Sebaihia M., Thomson N.R., Chaudhuri R.,
RA Henderson I.R., Sperandio V., Ravel J.;
RT "The pangenome structure of Escherichia coli: comparative genomic analysis
RT of E. coli commensal and pathogenic isolates.";
RL J. Bacteriol. 190:6881-6893(2008).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|PIRSR:PIRSR000089-1};
CC Note=Binds 1 FAD per dimer. {ECO:0000256|PIRSR:PIRSR000089-1};
CC -!- SIMILARITY: Belongs to the ETF alpha-subunit/FixB family.
CC {ECO:0000256|ARBA:ARBA00005817}.
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DR EMBL; CP000800; ABV21073.1; -; Genomic_DNA.
DR RefSeq; WP_001299097.1; NC_009801.1.
DR AlphaFoldDB; A7ZQL2; -.
DR SMR; A7ZQL2; -.
DR GeneID; 75205587; -.
DR KEGG; ecw:EcE24377A_3071; -.
DR HOGENOM; CLU_034178_0_1_6; -.
DR Proteomes; UP000001122; Chromosome.
DR GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.1220; TPP-binding domain; 1.
DR InterPro; IPR029035; DHS-like_NAD/FAD-binding_dom.
DR InterPro; IPR014730; ETF_a/b_N.
DR InterPro; IPR001308; ETF_a/FixB.
DR InterPro; IPR014731; ETF_asu_C.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR PANTHER; PTHR43153; ELECTRON TRANSFER FLAVOPROTEIN ALPHA; 1.
DR PANTHER; PTHR43153:SF5; PROTEIN FIXB-RELATED; 1.
DR Pfam; PF01012; ETF; 1.
DR Pfam; PF00766; ETF_alpha; 1.
DR PIRSF; PIRSF000089; Electra_flavoP_a; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF52467; DHS-like NAD/FAD-binding domain; 1.
PE 3: Inferred from homology;
KW Electron transport {ECO:0000256|ARBA:ARBA00022982};
KW FAD {ECO:0000256|PIRSR:PIRSR000089-1};
KW Flavoprotein {ECO:0000256|PIRSR:PIRSR000089-1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001122};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 41..128
FT /note="Electron transfer flavoprotein alpha/beta-subunit N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF01012"
FT DOMAIN 165..242
FT /note="Electron transfer flavoprotein alpha subunit C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF00766"
FT BINDING 199..200
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000089-1"
FT BINDING 251
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000089-1"
SQ SEQUENCE 286 AA; 30308 MW; FDADB6EDCFAC2962 CRC64;
MNIAIVTINQ ENAAIASWLA AQDFSGCTLA HWQIEPQPVV AEQVLDALVE QWQRTPADVV
LFPPGTFGDE LSTRLAWRLH GASICQVTSL DIPTVSVRKS HWGNALTATL QTEKRPLCLS
LARQAGAAKN ATLPSGMQQL NIVPGALPDW LVSTEDLKNV TRDPLAEARR VLVVGQGGEA
DNQEIAMLAE KLGAEVGYSR ARVMNGGVDA EKVIGISGHL LAPEVCIVVG ASGAAALMAG
VRNSKFVVAI NHDASAAVFS QADVGVVDDW KVVLEALVTN IHADCQ
//
