ID A8AEV3_CITK8 Unreviewed; 422 AA.
AC A8AEV3;
DT 23-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 23-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE RecName: Full=[acyl-carrier-protein] S-malonyltransferase {ECO:0000256|ARBA:ARBA00013258};
DE EC=2.3.1.39 {ECO:0000256|ARBA:ARBA00013258};
GN OrderedLocusNames=CKO_00866 {ECO:0000313|EMBL:ABV12016.1};
OS Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Citrobacter.
OX NCBI_TaxID=290338 {ECO:0000313|EMBL:ABV12016.1, ECO:0000313|Proteomes:UP000008148};
RN [1] {ECO:0000313|EMBL:ABV12016.1, ECO:0000313|Proteomes:UP000008148}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-895 / CDC 4225-83 / SGSC4696
RC {ECO:0000313|Proteomes:UP000008148};
RG The Citrobacter koseri Genome Sequencing Project;
RA McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S.,
RA Latreille P., Courtney L., Wang C., Pepin K., Bhonagiri V., Nash W.,
RA Johnson M., Thiruvilangam P., Wilson R.;
RL Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=holo-[ACP] + malonyl-CoA = CoA + malonyl-[ACP];
CC Xref=Rhea:RHEA:41792, Rhea:RHEA-COMP:9623, Rhea:RHEA-COMP:9685,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57384, ChEBI:CHEBI:64479,
CC ChEBI:CHEBI:78449; EC=2.3.1.39;
CC Evidence={ECO:0000256|ARBA:ARBA00000936};
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
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DR EMBL; CP000822; ABV12016.1; -; Genomic_DNA.
DR RefSeq; WP_000159201.1; NC_009792.1.
DR AlphaFoldDB; A8AEV3; -.
DR SMR; A8AEV3; -.
DR STRING; 290338.CKO_00866; -.
DR GeneID; 45135056; -.
DR KEGG; cko:CKO_00866; -.
DR HOGENOM; CLU_030558_1_0_6; -.
DR OrthoDB; 9808564at2; -.
DR Proteomes; UP000008148; Chromosome.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.250; Malonyl-CoA ACP transacylase, ACP-binding; 1.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 1.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR PANTHER; PTHR42681; MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR42681:SF1; MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE, MITOCHONDRIAL; 1.
DR Pfam; PF00698; Acyl_transf_1; 1.
DR SMART; SM00827; PKS_AT; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR SUPFAM; SSF55048; Probable ACP-binding domain of malonyl-CoA ACP transacylase; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Reference proteome {ECO:0000313|Proteomes:UP000008148};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 8..311
FT /note="Malonyl-CoA:ACP transacylase (MAT)"
FT /evidence="ECO:0000259|SMART:SM00827"
SQ SEQUENCE 422 AA; 46717 MW; 998AF045AAE811F3 CRC64;
MTKDVALMFP GSGSQYVGMA RWLYERYPQV RTLFDEASQI TERDMAALCL SGTLVQLAEP
TAMALAIYTT SVAHFVAWQQ FLAQTGVHVN LRYMLGHSLG EYAALTCSGA LSFSQALALV
AMRSRLASEI AREMDASTTI IKQGNQALVA AACEVAERET RQQVGIACFN SPQQFMLSGQ
NSAIIAAEQY LLDHDRQVEV VPLIGGVPYH SPLLKPCGQQ LRKALDRCEW RRPCCPVISN
VNAQPYPDTV TPVQWLEQQL SQPVQWQRSL TYLTGHLSPI AIEIGPQSVL KNLLLENRYP
APVYAFDNRH DRAQLALVLG DNMAVKTDPE AVRRQRITLL TNALTATRHH RAADVAASAQ
LKELLSRFFE RIQQIEQRGT SSEEDIAFLH ELLEQGFQLK GSSQAEIDAC HARLASDNGG
QA
//
