ID A8AKN4_CITK8 Unreviewed; 343 AA.
AC A8AKN4;
DT 23-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 23-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE RecName: Full=Cobalamin-independent methionine synthase MetE C-terminal/archaeal domain-containing protein {ECO:0000259|Pfam:PF01717};
GN OrderedLocusNames=CKO_02941 {ECO:0000313|EMBL:ABV14047.1};
OS Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Citrobacter.
OX NCBI_TaxID=290338 {ECO:0000313|EMBL:ABV14047.1, ECO:0000313|Proteomes:UP000008148};
RN [1] {ECO:0000313|EMBL:ABV14047.1, ECO:0000313|Proteomes:UP000008148}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-895 / CDC 4225-83 / SGSC4696
RC {ECO:0000313|Proteomes:UP000008148};
RG The Citrobacter koseri Genome Sequencing Project;
RA McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S.,
RA Latreille P., Courtney L., Wang C., Pepin K., Bhonagiri V., Nash W.,
RA Johnson M., Thiruvilangam P., Wilson R.;
RL Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the vitamin-B12 independent methionine synthase
CC family. {ECO:0000256|ARBA:ARBA00009553}.
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DR EMBL; CP000822; ABV14047.1; -; Genomic_DNA.
DR RefSeq; WP_012133760.1; NC_009792.1.
DR AlphaFoldDB; A8AKN4; -.
DR STRING; 290338.CKO_02941; -.
DR GeneID; 45136761; -.
DR KEGG; cko:CKO_02941; -.
DR HOGENOM; CLU_040013_3_0_6; -.
DR OrthoDB; 244285at2; -.
DR Proteomes; UP000008148; Chromosome.
DR GO; GO:0003871; F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0009086; P:methionine biosynthetic process; IEA:InterPro.
DR CDD; cd03311; CIMS_C_terminal_like; 1.
DR Gene3D; 3.20.20.210; -; 1.
DR InterPro; IPR002629; Met_Synth_C/arc.
DR InterPro; IPR016456; Met_Synthase_cat.
DR InterPro; IPR038071; UROD/MetE-like_sf.
DR PANTHER; PTHR30519; 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE; 1.
DR PANTHER; PTHR30519:SF0; 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE; 1.
DR Pfam; PF01717; Meth_synt_2; 1.
DR PIRSF; PIRSF005632; Met_synth_catalytic_prd; 1.
DR SUPFAM; SSF51726; UROD/MetE-like; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000008148};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 5..329
FT /note="Cobalamin-independent methionine synthase MetE C-
FT terminal/archaeal"
FT /evidence="ECO:0000259|Pfam:PF01717"
SQ SEQUENCE 343 AA; 38655 MW; 519FB14256C953A0 CRC64;
MKILLPTSTA GSLPKPSWLA QPETLWSPWK LQNEELIEGK QDALRLSLDD QLRAGIDIVS
DGEQTRQHFV TTFIEHLSGV DFEKRQIVKI RNRYDASVPT VVDAVARQKP VFVEDAKYLR
QLTRQPIKWA LPGPMTMIDT LYDAHYKSRE KLAWEFAKIL NQEARELEAA GVDIIQFDEP
AFNVFFDEVN DWGIAALEKA IEGLKCETAV HICYGYGIKA NTDWKKTLGS EWRQYEEAFP
KLQTSNIDII SLECHNSHVP MDLLELIRGK KVMVGAIDVA TNTIETPEEV ASTLRKALQF
VDADKLYPST NCGMAPLSRQ VAKGKLDALS AGAEIIRREL SAK
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