ID A8AXS7_STRGC Unreviewed; 339 AA.
AC A8AXS7;
DT 23-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 23-OCT-2007, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE SubName: Full=Transcriptional repressor MsmR {ECO:0000313|EMBL:ABV09581.1};
GN OrderedLocusNames=SGO_1306 {ECO:0000313|EMBL:ABV09581.1};
OS Streptococcus gordonii (strain Challis / ATCC 35105 / BCRC 15272 / CH1 /
OS DL1 / V288).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=467705 {ECO:0000313|EMBL:ABV09581.1, ECO:0000313|Proteomes:UP000001131};
RN [1] {ECO:0000313|EMBL:ABV09581.1, ECO:0000313|Proteomes:UP000001131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Challis / ATCC 35105 / BCRC 15272 / CH1 / DL1 / V288
RC {ECO:0000313|Proteomes:UP000001131};
RX PubMed=17720781; DOI=10.1128/JB.01023-07;
RA Vickerman M.M., Iobst S., Jesionowski A.M., Gill S.R.;
RT "Genome-wide transcriptional changes in Streptococcus gordonii in response
RT to competence signaling peptide.";
RL J. Bacteriol. 189:7799-7807(2007).
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DR EMBL; CP000725; ABV09581.1; -; Genomic_DNA.
DR RefSeq; WP_012000695.1; NC_009785.1.
DR AlphaFoldDB; A8AXS7; -.
DR STRING; 467705.SGO_1306; -.
DR KEGG; sgo:SGO_1306; -.
DR eggNOG; COG1609; Bacteria.
DR HOGENOM; CLU_037628_6_0_9; -.
DR Proteomes; UP000001131; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06291; PBP1_Qymf-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR001761; Peripla_BP/Lac1_sug-bd_dom.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR PANTHER; PTHR30146:SF95; RIBOSE OPERON REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF00532; Peripla_BP_1; 1.
DR PRINTS; PR00036; HTHLACI.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000001131};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 9..63
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT DOMAIN 9..53
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
SQ SEQUENCE 339 AA; 38172 MW; F941E599659B0D40 CRC64;
MQGKSRTSIT MKDVASRAGV SVGTVSRVIN NEKGIKKVTL KKVQEAIEEL NYIPDNYARG
LKTNKSSNIA LIIPTIWHPF FSELAYYVEK ELLKNQYKLF ICNADGDVKN EIEYIQMLEK
NKVDGIIAVT YSDVDKYVSS SLPFVSFDRH FSENVSYVTS ENYKGGQMAA EELLNRGAKQ
LAYIGSTNIH ENETKQRELG FCEKLMSMGH SVLKLDMSEP LVEPEKQIEK FLLEHSTIDG
IFAINDFMAI KVMKVMEKFG KKAPQDYQII GFDGLRNAAD QTYLLSTIAQ PLDKIAQASV
KLLLQLISKE KAVLSRVLLP VYFAEGGTTK KIQKSLDKK
//
