ID A8B4N8_GIAIC Unreviewed; 322 AA.
AC A8B4N8;
DT 13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2007, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Protein kinase {ECO:0000313|EMBL:EDO81976.1};
GN ORFNames=GL50803_32958 {ECO:0000313|EMBL:EDO81976.1};
OS Giardia intestinalis (strain ATCC 50803 / WB clone C6) (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=184922 {ECO:0000313|EMBL:EDO81976.1};
RN [1] {ECO:0000313|EMBL:EDO81976.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WB C6 {ECO:0000313|EMBL:EDO81976.1};
RX PubMed=17901334; DOI=10.1126/science.1143837;
RA Morrison H.G., McArthur A.G., Gillin F.D., Aley S.B., Adam R.D.,
RA Olsen G.J., Best A.A., Cande W.Z., Chen F., Cipriano M.J., Davids B.J.,
RA Dawson S.C., Elmendorf H.G., Hehl A.B., Holder M.E., Huse S.M., Kim U.U.,
RA Lasek-Nesselquist E., Manning G., Nigam A., Nixon J.E., Palm D.,
RA Passamaneck N.E., Prabhu A., Reich C.I., Reiner D.S., Samuelson J.,
RA Svard S.G., Sogin M.L.;
RT "Genomic minimalism in the early diverging intestinal parasite Giardia
RT lamblia.";
RL Science 317:1921-1926(2007).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDO81976.1}.
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DR EMBL; AACB02000002; EDO81976.1; -; Genomic_DNA.
DR RefSeq; XP_001709650.1; XM_001709598.1.
DR AlphaFoldDB; A8B4N8; -.
DR STRING; 184922.A8B4N8; -.
DR EnsemblProtists; EDO81976; EDO81976; GL50803_32958.
DR VEuPathDB; GiardiaDB:GL50803_32958; -.
DR HOGENOM; CLU_864476_0_0_1; -.
DR OMA; MERESCM; -.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR PANTHER; PTHR24184:SF11; ANK_REP_REGION DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24184; SI:CH211-189E2.2; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 2.
DR SMART; SM00248; ANK; 6.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:EDO81976.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000313|EMBL:EDO81976.1}.
FT REPEAT 296..322
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT COILED 6..65
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 322 AA; 35187 MW; B7AE0C5C9BBB93DB CRC64;
MLKYECGSLK AALNSANARI ATLEAALDAR STEMVSQSTE TASLKDALED QCKEHLAMIK
ALENRFTEFS GGMNTSSSQI NLSALPQLIR AAHTNNMETV RMLANKRNYI GQRDEQGMTA
LMHAAQQGHI GPVELLVRKE RGLKDKSGWT ALMHAAHGNH LEVIEILIPY EHRKRSKNNH
TALMIAVKKG HIEAASLLVS YEKNLIDDEG KTALVIAAEA GHEALMETID PTDDRGVTAL
MRAVDRGDMA TAKALVALQR GRVAHGETAL MQAVTYDNIN GIKLLLPHES GMHDRYGATA
LMKAAYKGYL EAVKLLIKKK VG
//
