ID A8BE06_GIAIC Unreviewed; 618 AA.
AC A8BE06;
DT 13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2007, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Ankyrin repeat protein 1 {ECO:0000313|EMBL:KAE8305859.1};
DE SubName: Full=Protein 21.1 {ECO:0000313|EMBL:EDO79887.1};
GN ORFNames=GL50803_0014238 {ECO:0000313|EMBL:KAE8305859.1},
GN GL50803_14238 {ECO:0000313|EMBL:EDO79887.1};
OS Giardia intestinalis (strain ATCC 50803 / WB clone C6) (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=184922 {ECO:0000313|EMBL:EDO79887.1};
RN [1] {ECO:0000313|EMBL:EDO79887.1, ECO:0000313|Proteomes:UP000001548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50803 / WB clone C6 {ECO:0000313|Proteomes:UP000001548},
RC and WB C6 {ECO:0000313|EMBL:EDO79887.1};
RX PubMed=17901334; DOI=10.1126/science.1143837;
RA Morrison H.G., McArthur A.G., Gillin F.D., Aley S.B., Adam R.D.,
RA Olsen G.J., Best A.A., Cande W.Z., Chen F., Cipriano M.J., Davids B.J.,
RA Dawson S.C., Elmendorf H.G., Hehl A.B., Holder M.E., Huse S.M., Kim U.U.,
RA Lasek-Nesselquist E., Manning G., Nigam A., Nixon J.E., Palm D.,
RA Passamaneck N.E., Prabhu A., Reich C.I., Reiner D.S., Samuelson J.,
RA Svard S.G., Sogin M.L.;
RT "Genomic minimalism in the early diverging intestinal parasite Giardia
RT lamblia.";
RL Science 317:1921-1926(2007).
RN [2] {ECO:0000313|EMBL:KAE8305859.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=WB C6 {ECO:0000313|EMBL:KAE8305859.1};
RA Xu F., Jex A., Svard S.G.;
RT "New Giardia intestinalis WB genome in near-complete chromosomes.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDO79887.1}.
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DR EMBL; AACB02000013; EDO79887.1; -; Genomic_DNA.
DR EMBL; AACB03000001; KAE8305859.1; -; Genomic_DNA.
DR RefSeq; XP_001707561.1; XM_001707509.1.
DR AlphaFoldDB; A8BE06; -.
DR STRING; 184922.A8BE06; -.
DR EnsemblProtists; EDO79887; EDO79887; GL50803_14238.
DR GeneID; 5700463; -.
DR KEGG; gla:GL50803_0014238; -.
DR VEuPathDB; GiardiaDB:GL50803_14238; -.
DR HOGENOM; CLU_442432_0_0_1; -.
DR InParanoid; A8BE06; -.
DR OMA; GHYSCIS; -.
DR Proteomes; UP000001548; Chromosome 5.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR PANTHER; PTHR24184:SF11; ANK_REP_REGION DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24184; SI:CH211-189E2.2; 1.
DR Pfam; PF12796; Ank_2; 2.
DR SMART; SM00248; ANK; 7.
DR SUPFAM; SSF48403; Ankyrin repeat; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000001548};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REGION 265..287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 323..347
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 230..264
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 265..280
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 618 AA; 66907 MW; F12FEA26D948A619 CRC64;
MCAMASKQED LLPVLIPSSS GMATENGEYA ITLAAELEFL PGVLAVLPYE HHYRNRDGDS
ALHILARKGI VDIIPQCAQY LERARDATGR IPIDVAAEHN SVAFLKASIE NKLGLTADDV
LRTFCAARHA GRQEAMDCLR EYIFVEPVEC LCYRCSNVLD FPSNSSSRLG TPIVSRYSSI
CRTPLSFKSI RSLGSLSAER RPSLRSPCLS PRLSNSVETT SIGIQVSTAC QNCTESAQIY
EQQIAELNDR LSALTAQLNT FSQRSPQVST TLPHCTESNS GFSERRQKQR DIVEAAALSF
SPLQEASKAQ TRELISVVTP TVNRITDDPH PSVPSSPLPS SSLCSSQGSN PTVLRFSGFR
GITELALSKV GSLKNSSPHL EDMGSLYEAP DMHTNMTDLM RAACSGNVGL VGKLIATQSR
HQTESGYTAL MFACRIGNLA AAKMLLPYEA GMQTKTGSTA LMEACASGSK ELATLLLIEG
GIYRKDGWSA LMSAARAGLP DIVRCLLPVE SGRATLGGVT ALMKAVEQGH YSCISMLIPS
EIHFRRKDGR TAIDIARELN NTGIIGLLED YINNHPVSLS DHQTTTERDS NQLTSSEMEL
LADIDEYIIM GDGASDKC
//
