ID A8BPT0_GIAIC Unreviewed; 804 AA.
AC A8BPT0;
DT 13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2007, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=Ankyrin repeat protein 1 {ECO:0000313|EMBL:KAE8304355.1};
DE SubName: Full=Protein 21.1 {ECO:0000313|EMBL:EDO77992.1};
GN ORFNames=GL50803_0014254 {ECO:0000313|EMBL:KAE8304355.1},
GN GL50803_14254 {ECO:0000313|EMBL:EDO77992.1};
OS Giardia intestinalis (strain ATCC 50803 / WB clone C6) (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=184922 {ECO:0000313|EMBL:EDO77992.1};
RN [1] {ECO:0000313|EMBL:EDO77992.1, ECO:0000313|Proteomes:UP000001548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50803 / WB clone C6 {ECO:0000313|Proteomes:UP000001548},
RC and WB C6 {ECO:0000313|EMBL:EDO77992.1};
RX PubMed=17901334; DOI=10.1126/science.1143837;
RA Morrison H.G., McArthur A.G., Gillin F.D., Aley S.B., Adam R.D.,
RA Olsen G.J., Best A.A., Cande W.Z., Chen F., Cipriano M.J., Davids B.J.,
RA Dawson S.C., Elmendorf H.G., Hehl A.B., Holder M.E., Huse S.M., Kim U.U.,
RA Lasek-Nesselquist E., Manning G., Nigam A., Nixon J.E., Palm D.,
RA Passamaneck N.E., Prabhu A., Reich C.I., Reiner D.S., Samuelson J.,
RA Svard S.G., Sogin M.L.;
RT "Genomic minimalism in the early diverging intestinal parasite Giardia
RT lamblia.";
RL Science 317:1921-1926(2007).
RN [2] {ECO:0000313|EMBL:KAE8304355.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=WB C6 {ECO:0000313|EMBL:KAE8304355.1};
RA Xu F., Jex A., Svard S.G.;
RT "New Giardia intestinalis WB genome in near-complete chromosomes.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDO77992.1}.
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DR EMBL; AACB02000031; EDO77992.1; -; Genomic_DNA.
DR EMBL; AACB03000002; KAE8304355.1; -; Genomic_DNA.
DR RefSeq; XP_001705666.1; XM_001705614.1.
DR AlphaFoldDB; A8BPT0; -.
DR STRING; 184922.A8BPT0; -.
DR EnsemblProtists; EDO77992; EDO77992; GL50803_14254.
DR GeneID; 5698551; -.
DR KEGG; gla:GL50803_0014254; -.
DR VEuPathDB; GiardiaDB:GL50803_14254; -.
DR HOGENOM; CLU_006674_0_0_1; -.
DR InParanoid; A8BPT0; -.
DR OMA; GPHERGI; -.
DR Proteomes; UP000001548; Chromosome 4.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR PANTHER; PTHR24184:SF11; ANK_REP_REGION DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24184; SI:CH211-189E2.2; 1.
DR Pfam; PF12796; Ank_2; 3.
DR SMART; SM00248; ANK; 9.
DR SUPFAM; SSF48403; Ankyrin repeat; 2.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000001548};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 653..685
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 202..226
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 275..295
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 202..222
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 277..295
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 804 AA; 87538 MW; 60456357DDD6BB55 CRC64;
MSTELAQWFA AARTGDEQYI LTSMGTFAGS KNEKGETALM IATYNNHARI VSRLCPYEVR
QSDNSGKAAI HIAVEQNNYD TCTALGPHER GILIENGMNP YHLAARLGKA RAMDALSIFF
GMERDFDGLS VLEHAIIGES EECLRHALNN RKVTPKDIAN AKAYAEQHGL SSKMIGIIDE
KLREYGDSST SSMVGVHLSQ RYTPSARSQP QSDHTSINFP DEGSLHTDDH VQEMRQITGS
FRCVPVNPRS EDCARIDELL AAKDELLREH MAERLSPTTR SRSVSPPVSP HLSRVPNFSV
ADTDSAPNAA VTAAVLPTSP LGINSFRSPP PSQDIDAGDT IDDIIDALGH VSRQTKLNED
MGVPMPRREP PQIARTPLEP LEKLTGSFTA TAFADESVKK TPEIPKLLPD NYEYKDYPNN
SGTIDMNKKY KDSPRDAINK GLEKLTASQR IVDKGLTSTT AILASEYDPR TSQYKVAIDR
ANEIIRSSTD PVGPYAHRAQ SQSKNKAVRK AVAVLEDDAL PTVEEIQRAT KTNVTASAIV
PPLATTIPDD EGRRLTSSFI GGQPLMGNAP DLVSSLRFRN STLQDPVART QCTLPVVEET
ISVEDLIASH KQNHPQDRST PGRFTSLMRA AIENDIAAAK MLVISFARVQ DPEGKTALMY
AAERGHEEIA NLLLPFEGGM QLKNGGTALM HALGNGHLNV AAMLMSCDGG LAMNDGWTAL
MSAATINADN IVVGLLEKEA GMVCNCSHKE GEGYCACMIA AKKNNLESLR LLAPREGQIT
NFRGQNALSF AKTSEARELL SLFH
//
