ID A8E611_XENLA Unreviewed; 343 AA.
AC A8E611;
DT 13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2007, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE RecName: Full=Apolipoprotein A-V {ECO:0000256|ARBA:ARBA00040758};
DE AltName: Full=Apolipoprotein A5 {ECO:0000256|ARBA:ARBA00042594};
GN Name=apoa5.L {ECO:0000313|RefSeq:NP_001104214.1,
GN ECO:0000313|Xenbase:XB-GENE-1022412};
GN Synonyms=apoa5 {ECO:0000313|RefSeq:NP_001104214.1,
GN ECO:0000313|Xenbase:XB-GENE-1022412}, LOC100126643
GN {ECO:0000313|EMBL:AAI53794.1};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|EMBL:AAI53794.1};
RN [1] {ECO:0000313|RefSeq:NP_001104214.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12454917; DOI=10.1002/dvdy.10174;
RA Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA Richardson P.;
RT "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT initiative.";
RL Dev. Dyn. 225:384-391(2002).
RN [2] {ECO:0000313|EMBL:AAI53794.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Intestine {ECO:0000313|EMBL:AAI53794.1}, and Oocytes
RC {ECO:0000313|EMBL:AAI69462.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:NP_001104214.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network
CC {ECO:0000256|ARBA:ARBA00004601}. Late endosome
CC {ECO:0000256|ARBA:ARBA00004603}.
CC -!- SIMILARITY: Belongs to the apolipoprotein A1/A4/E family.
CC {ECO:0000256|ARBA:ARBA00008788}.
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DR EMBL; BC153793; AAI53794.1; -; mRNA.
DR EMBL; BC169462; AAI69462.1; -; mRNA.
DR EMBL; BC169464; AAI69464.1; -; mRNA.
DR RefSeq; NP_001104214.1; NM_001110744.1.
DR GeneID; 100126643; -.
DR KEGG; xla:100126643; -.
DR AGR; Xenbase:XB-GENE-1022412; -.
DR CTD; 100126643; -.
DR Xenbase; XB-GENE-1022412; apoa5.L.
DR OrthoDB; 4355748at2759; -.
DR Proteomes; UP000186698; Chromosome 7L.
DR Bgee; 100126643; Expressed in liver and 1 other cell type or tissue.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0005770; C:late endosome; IEA:UniProtKB-SubCell.
DR GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR GO; GO:0006869; P:lipid transport; IEA:InterPro.
DR GO; GO:0042157; P:lipoprotein metabolic process; IEA:InterPro.
DR Gene3D; 1.20.120.20; Apolipoprotein; 2.
DR InterPro; IPR000074; ApoA_E.
DR PANTHER; PTHR18976; APOLIPOPROTEIN; 1.
DR PANTHER; PTHR18976:SF13; APOLIPOPROTEIN A-V; 1.
DR Pfam; PF01442; Apolipoprotein; 2.
DR SUPFAM; SSF58113; Apolipoprotein A-I; 2.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|SAM:SignalP, ECO:0000313|RefSeq:NP_001104214.1}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..343
FT /note="Apolipoprotein A-V"
FT /evidence="ECO:0000256|SAM:SignalP,
FT ECO:0000313|RefSeq:NP_001104214.1"
FT /id="PRO_5033207371"
SQ SEQUENCE 343 AA; 40260 MW; 09821ABF61C0DE86 CRC64;
MVKTSWLFLL LLVTLTGSKA ENTRSGFWEY LSQLTSDKDK WDLQQNAARE INTLKSSFQN
GVNYVGKFLG PLKNGFQQRL YQDTDGLQRL ISRELQELRR KIYPYMDEAH QKISKNLEQL
QSRLLPYTSE LKDQVEWGAQ ELHLQLRPYK DDLKTWKMDK LAEHLQDRII LHTGRVKEGF
YPLAERLVEE IHHAAEELHL NLSPHTHTTQ DKLSQQVQEL SQKLTKNARD LHEKIHKNLD
ELKQQLVSYP HQIKQQFPNG HSAEHVAPYV DEMAAQVQKE VEEFQRSTKM QIEDFTRTIN
KEAEEMQNKL SPASWDFQDS VSTVEDVQEK LDSLWRDIAQ SLD
//
