ID A8F6R2_PSELT Unreviewed; 356 AA.
AC A8F6R2;
DT 13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2007, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Alanine racemase domain protein {ECO:0000313|EMBL:ABV33846.1};
GN OrderedLocusNames=Tlet_1288 {ECO:0000313|EMBL:ABV33846.1};
OS Pseudothermotoga lettingae (strain ATCC BAA-301 / DSM 14385 / NBRC 107922 /
OS TMO) (Thermotoga lettingae).
OC Bacteria; Thermotogota; Thermotogae; Thermotogales; Thermotogaceae;
OC Pseudothermotoga.
OX NCBI_TaxID=416591 {ECO:0000313|EMBL:ABV33846.1, ECO:0000313|Proteomes:UP000002016};
RN [1] {ECO:0000313|EMBL:ABV33846.1, ECO:0000313|Proteomes:UP000002016}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-301 / DSM 14385 / NBRC 107922 / TMO
RC {ECO:0000313|Proteomes:UP000002016};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Foster B., Bruce D., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Mikhailova N., Nelson K., Gogarten J.P., Noll K.,
RA Richardson P.;
RT "Complete sequence of Thermotoga lettingae TMO.";
RL Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABV33846.1, ECO:0000313|Proteomes:UP000002016}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-301 / DSM 14385 / NBRC 107922 / TMO
RC {ECO:0000313|Proteomes:UP000002016};
RX PubMed=19307556; DOI=10.1073/pnas.0901260106;
RA Zhaxybayeva O., Swithers K.S., Lapierre P., Fournier G.P., Bickhart D.M.,
RA DeBoy R.T., Nelson K.E., Nesbo C.L., Doolittle W.F., Gogarten J.P.,
RA Noll K.M.;
RT "On the chimeric nature, thermophilic origin, and phylogenetic placement of
RT the Thermotogales.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:5865-5870(2009).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
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DR EMBL; CP000812; ABV33846.1; -; Genomic_DNA.
DR RefSeq; WP_012003322.1; NZ_BSDV01000001.1.
DR AlphaFoldDB; A8F6R2; -.
DR STRING; 416591.Tlet_1288; -.
DR KEGG; tle:Tlet_1288; -.
DR eggNOG; COG3457; Bacteria.
DR HOGENOM; CLU_067103_0_0_0; -.
DR OrthoDB; 504078at2; -.
DR Proteomes; UP000002016; Chromosome.
DR GO; GO:0047661; F:amino-acid racemase activity; IEA:UniProt.
DR CDD; cd06815; PLPDE_III_AR_like_1; 1.
DR Gene3D; 3.20.20.10; Alanine racemase; 1.
DR InterPro; IPR001608; Ala_racemase_N.
DR InterPro; IPR029066; PLP-binding_barrel.
DR PANTHER; PTHR30511; ALANINE RACEMASE; 1.
DR PANTHER; PTHR30511:SF3; LYSINE RACEMASE; 1.
DR Pfam; PF01168; Ala_racemase_N; 1.
DR SUPFAM; SSF51419; PLP-binding barrel; 1.
PE 4: Predicted;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000002016}.
FT DOMAIN 6..224
FT /note="Alanine racemase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01168"
SQ SEQUENCE 356 AA; 39685 MW; 6F8A3C4AA17177DB CRC64;
MPRLYINLRL LEKNTKEVLS LCSKHNVELI GVTKVSLGDP QVAQCIRNAG VNIIGESRVE
NIKRMVKSGI NRPFMMLRIP AISQLEEIVD LCDYILVSEL KTVEAIEEIC KNAGKSVNLI
YMVDVGDLRE GVWYKQAEEE ICKAVKICKT SRIIGVGTNL GCYGGILPTN ENMAKLVYIR
DKIEQRTNTH LPIVSGGNTA ALRLLEHSDL PEGVNQYRVG EAIMLGTDVT NNRKIDWLEQ
KTVVLEAEVI EMKTKPSVPE GQSGLDAFGR QPVFVDKGLR KRAILALGEQ DTVPKHLKPL
DKNAEVIHAS SDHTIVDITE VQRQINVGDT MKFTLSYAAL LRAMTCPHVE KIYRGE
//
