ID   A8L9J2_FRASN            Unreviewed;       477 AA.
AC   A8L9J2;
DT   04-DEC-2007, integrated into UniProtKB/TrEMBL.
DT   04-DEC-2007, sequence version 1.
DT   27-MAR-2024, entry version 70.
DE   SubName: Full=AMP-dependent synthetase and ligase {ECO:0000313|EMBL:ABW13695.1};
GN   ORFNames=Franean1_4311 {ECO:0000313|EMBL:ABW13695.1};
OS   Frankia sp. (strain EAN1pec).
OC   Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae; Frankia.
OX   NCBI_TaxID=298653 {ECO:0000313|EMBL:ABW13695.1};
RN   [1] {ECO:0000313|EMBL:ABW13695.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=EAN1.pec {ECO:0000313|EMBL:ABW13695.1};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N.,
RA   Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T.,
RA   Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Kim E., Rawnsley T., Niemann J., Benson D.R., Huang Y.,
RA   Mastronunzio J., Bassi C.A., Tisa L.S., Richardson P.;
RT   "Complete sequence of Frankia sp. EAN1pec.";
RL   Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000820; ABW13695.1; -; Genomic_DNA.
DR   AlphaFoldDB; A8L9J2; -.
DR   STRING; 298653.Franean1_4311; -.
DR   KEGG; fre:Franean1_4311; -.
DR   eggNOG; COG0318; Bacteria.
DR   HOGENOM; CLU_000022_59_7_11; -.
DR   GO; GO:0016877; F:ligase activity, forming carbon-sulfur bonds; IEA:UniProt.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR   PANTHER; PTHR43767:SF1; NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Ligase {ECO:0000313|EMBL:ABW13695.1}.
FT   DOMAIN          13..346
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          397..470
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
SQ   SEQUENCE   477 AA;  51266 MW;  5B929F9194FF7336 CRC64;
     MKWETIPEMV LSAADRFDDA EAVVDGALRL TYTELVDRIR AAAGSFAAAG VGKGDRVAIW
     APNSAEWIIA AFGLLTAGGV LVPVNTRYKA EEADDILRRS GAKMVLVQEG FLGQVYAGTT
     CVPAVDIKSG FLSSGAPLDG PVGQDGDETA DILFTSGTTG RPKGVMMNHR QTLRLYEEWC
     ELADLREGDR YLCVNPFFHN FGYKAGLVAA LIRGATIVPM AVFEIDKLIE LVEREKITML
     PGPPTLYHSL LAVPDKTALA SLRCAVTGSA DIPVELIRRM RDELPFRSIM TGYGLTEAGT
     ATASRPGDSF VDIATTVGTA CDGVEVAVAD DGEVLVRGYT VMQGYLDDPV ATAEAIDPDG
     WLHTGDLGTL DERGHLRIVG RKKDMFIVGG FNAYPAEIEG FLLEHPAVAQ AAVIGVPDER
     MGEVGKAFVV RRAPVTADEL ITWSKGRMAG FKVPRTVEFL ESLPLNASGK VMKDNLR
//