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Database: UniProt
Entry: A8LIX5_DINSH
LinkDB: A8LIX5_DINSH
Original site: A8LIX5_DINSH 
ID   A8LIX5_DINSH            Unreviewed;       194 AA.
AC   A8LIX5;
DT   04-DEC-2007, integrated into UniProtKB/TrEMBL.
DT   04-DEC-2007, sequence version 1.
DT   27-MAR-2024, entry version 73.
DE   RecName: Full=TIGR02281 family clan AA aspartic protease {ECO:0008006|Google:ProtNLM};
GN   OrderedLocusNames=Dshi_1347 {ECO:0000313|EMBL:ABV93089.1};
OS   Dinoroseobacter shibae (strain DSM 16493 / NCIMB 14021 / DFL 12).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Dinoroseobacter.
OX   NCBI_TaxID=398580 {ECO:0000313|EMBL:ABV93089.1, ECO:0000313|Proteomes:UP000006833};
RN   [1] {ECO:0000313|Proteomes:UP000006833}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16493 / NCIMB 14021 / DFL 12
RC   {ECO:0000313|Proteomes:UP000006833};
RX   PubMed=19741735; DOI=10.1038/ismej.2009.94;
RA   Wagner-Dobler I., Ballhausen B., Berger M., Brinkhoff T., Buchholz I.,
RA   Bunk B., Cypionka H., Daniel R., Drepper T., Gerdts G., Hahnke S., Han C.,
RA   Jahn D., Kalhoefer D., Kiss H., Klenk H.P., Kyrpides N., Liebl W.,
RA   Liesegang H., Meincke L., Pati A., Petersen J., Piekarski T.,
RA   Pommerenke C., Pradella S., Pukall R., Rabus R., Stackebrandt E., Thole S.,
RA   Thompson L., Tielen P., Tomasch J., von Jan M., Wanphrut N., Wichels A.,
RA   Zech H., Simon M.;
RT   "The complete genome sequence of the algal symbiont Dinoroseobacter shibae:
RT   a hitchhiker's guide to life in the sea.";
RL   ISME J. 4:61-77(2010).
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DR   EMBL; CP000830; ABV93089.1; -; Genomic_DNA.
DR   RefSeq; WP_012178019.1; NC_009952.1.
DR   AlphaFoldDB; A8LIX5; -.
DR   STRING; 398580.Dshi_1347; -.
DR   MEROPS; A32.002; -.
DR   KEGG; dsh:Dshi_1347; -.
DR   eggNOG; COG3577; Bacteria.
DR   HOGENOM; CLU_099411_0_1_5; -.
DR   OrthoDB; 7595324at2; -.
DR   Proteomes; UP000006833; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   CDD; cd05483; retropepsin_like_bacteria; 1.
DR   Gene3D; 2.40.70.10; Acid Proteases; 1.
DR   InterPro; IPR001969; Aspartic_peptidase_AS.
DR   InterPro; IPR011969; Clan_AA_Asp_peptidase_C.
DR   InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR   InterPro; IPR034122; Retropepsin-like_bacterial.
DR   NCBIfam; TIGR02281; clan_AA_DTGA; 1.
DR   Pfam; PF13975; gag-asp_proteas; 1.
DR   SUPFAM; SSF50630; Acid proteases; 1.
DR   PROSITE; PS00141; ASP_PROTEASE; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006833};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        9..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        33..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   194 AA;  21014 MW;  255067375D6F0CD6 CRC64;
     MSEISVPNLI YLILLLLFIG GGTLMAFRGQ LGALVRTATS WALLFALVVI GYGVFSDQRS
     PLPRQSVFAE TGRVEIPRAM DGHYHVVLDV NGAPIEFIVD TGASDMVLSL QDAARAGINP
     ENLMFSGLAM TANGRVETAP VRLKEVRLGG ISDENVRAVV NGGEMHRSLL GMSYLNSFDR
     IEINEGRLIL ERGV
//
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