ID A8PK22_9COXI Unreviewed; 178 AA.
AC A8PK22;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=phospholipase D {ECO:0000256|ARBA:ARBA00012027};
DE EC=3.1.4.4 {ECO:0000256|ARBA:ARBA00012027};
GN ORFNames=RICGR_0232 {ECO:0000313|EMBL:EDP46030.1};
OS Rickettsiella grylli.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales; Coxiellaceae;
OC Rickettsiella.
OX NCBI_TaxID=59196 {ECO:0000313|EMBL:EDP46030.1, ECO:0000313|Proteomes:UP000054075};
RN [1] {ECO:0000313|EMBL:EDP46030.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Seshadri R., Federici B.A.;
RL Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EDP46030.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Myers G.S.;
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-
CC sn-glycero-3-phosphate + choline + H(+); Xref=Rhea:RHEA:14445,
CC ChEBI:CHEBI:15354, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57643, ChEBI:CHEBI:58608; EC=3.1.4.4;
CC Evidence={ECO:0000256|ARBA:ARBA00000798};
CC -!- SIMILARITY: Belongs to the phospholipase D family.
CC {ECO:0000256|ARBA:ARBA00008664}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDP46030.1}.
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DR EMBL; AAQJ02000001; EDP46030.1; -; Genomic_DNA.
DR AlphaFoldDB; A8PK22; -.
DR STRING; 59196.RICGR_0232; -.
DR eggNOG; COG1502; Bacteria.
DR OrthoDB; 5294698at2; -.
DR Proteomes; UP000054075; Unassembled WGS sequence.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006793; P:phosphorus metabolic process; IEA:UniProt.
DR CDD; cd09170; PLDc_Nuc; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 1.
DR InterPro; IPR025202; PLD-like_dom.
DR InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR PANTHER; PTHR43856; CARDIOLIPIN HYDROLASE; 1.
DR PANTHER; PTHR43856:SF1; MITOCHONDRIAL CARDIOLIPIN HYDROLASE; 1.
DR Pfam; PF13091; PLDc_2; 1.
DR SMART; SM00155; PLDc; 1.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 1.
DR PROSITE; PS50035; PLD; 1.
PE 3: Inferred from homology;
KW Endonuclease {ECO:0000313|EMBL:EDP46030.1};
KW Hydrolase {ECO:0000313|EMBL:EDP46030.1};
KW Nuclease {ECO:0000313|EMBL:EDP46030.1}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..178
FT /note="phospholipase D"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002727758"
FT DOMAIN 113..140
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
SQ SEQUENCE 178 AA; 20117 MW; 6C4855C639547B4D CRC64;
MLKKLFLVFL LSPCLITTSF AINKIKNCPT LQACFTPGQN CTEEITDVID AAKKSIFVQA
YSFTSAAIAE HLVAAKKRGV NVNVILDKSQ RTQRYSASHF LIHQHIPCWI DYKPAIAHNK
VMIIDEKEVI TGSFNFTKAA QAHNAENLLV IRDHSLAQLY LKNWQRRQAV SRSLNPHI
//
