ID A8QD58_MALGO Unreviewed; 688 AA.
AC A8QD58;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE RecName: Full=Golgi apparatus membrane protein TVP38 {ECO:0000256|ARBA:ARBA00013533};
DE AltName: Full=Golgi apparatus membrane protein tvp38 {ECO:0000256|ARBA:ARBA00020673};
GN ORFNames=MGL_4126 {ECO:0000313|EMBL:EDP41577.1};
OS Malassezia globosa (strain ATCC MYA-4612 / CBS 7966) (Dandruff-associated
OS fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Malasseziomycetes; Malasseziales; Malasseziaceae; Malassezia.
OX NCBI_TaxID=425265 {ECO:0000313|EMBL:EDP41577.1, ECO:0000313|Proteomes:UP000008837};
RN [1] {ECO:0000313|EMBL:EDP41577.1, ECO:0000313|Proteomes:UP000008837}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4612 / CBS 7966 {ECO:0000313|Proteomes:UP000008837};
RX PubMed=18000048; DOI=10.1073/pnas.0706756104;
RA Xu J., Saunders C.W., Hu P., Grant R.A., Boekhout T., Kuramae E.E.,
RA Kronstad J.W., Deangelis Y.M., Reeder N.L., Johnstone K.R., Leland M.,
RA Fieno A.M., Begley W.M., Sun Y., Lacey M.P., Chaudhary T., Keough T.,
RA Chu L., Sears R., Yuan B., Dawson T.L.Jr.;
RT "Dandruff-associated Malassezia genomes reveal convergent and divergent
RT virulence traits shared with plant and human fungal pathogens.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:18730-18735(2007).
CC -!- FUNCTION: Golgi membrane protein involved in vesicular trafficking and
CC spindle migration. {ECO:0000256|ARBA:ARBA00002978}.
CC -!- SIMILARITY: Belongs to the TVP38/TMEM64 family.
CC {ECO:0000256|ARBA:ARBA00008640}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDP41577.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAYY01000020; EDP41577.1; -; Genomic_DNA.
DR RefSeq; XP_001728791.1; XM_001728739.1.
DR AlphaFoldDB; A8QD58; -.
DR GeneID; 5853097; -.
DR KEGG; mgl:MGL_4126; -.
DR VEuPathDB; FungiDB:MGL_4126; -.
DR InParanoid; A8QD58; -.
DR OMA; WIYWARA; -.
DR OrthoDB; 1365790at2759; -.
DR Proteomes; UP000008837; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR032816; VTT_dom.
DR PANTHER; PTHR47549:SF3; GOLGI APPARATUS MEMBRANE PROTEIN TVP38; 1.
DR PANTHER; PTHR47549; GOLGI APPARATUS MEMBRANE PROTEIN TVP38-RELATED; 1.
DR Pfam; PF09335; SNARE_assoc; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008837};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 367..389
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 401..419
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 439..460
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 570..588
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 425..539
FT /note="VTT"
FT /evidence="ECO:0000259|Pfam:PF09335"
FT REGION 1..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 172..242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 598..642
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..39
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 68..114
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 178..203
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 211..225
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 599..616
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 688 AA; 75259 MW; 189AA26186F896CF CRC64;
MSLHGPAEVP KRSDSATTHR QRRTPSLRVQ TTQLRSFSYD SEPGARRGQV PVSSSAAAAA
AAAAGQSATG RSRRSTMTSH GQLPSAGGAG TVGGSTSRTQ SPLSVLSPRT PSSHAHTRLF
GRAAAYAAQS LVDVVTRSLS PSSTHGYASI LFDMPTASSP ISSIADWDHR HADAGTSSND
HRTAAHSTTS SANGPNGGSD IRHPVQQHQH HAHHHVNDDD RRSSSDTTAG SAPAYALAGD
DDEVQLLRTH ARKSTHSEHS IPMDDIVAPK ARHGAVWLHP KPSKASAAST HRRQRNRQAE
HAARWTAEHA WARLRTGLSL LANPRELAAS VHQHVHAQWI YWARAFRDPM TDQRIWWPPW
LASYVPLLIW VGISVMSTTM VMLFHVQLFH ALDVLSTTLR SLGLVGRVLF GMIIFVLTFP
PMPLYSTMIV LSGFAFGMWQ GFLVSYVAAL TGAASVFVLS RTHLRAWMMR LLAHAGGLQR
VIRAIELRPQ LLFLVRLAPY PYNLLNMLLA SSHVLTFRTY ITCTALALPK LLVHTSIGAS
IESFASYHSA ANETQGADPS HKKTNTVRQV FGGFGIALCV GIFLYLYYVT RRAVDTLDSD
EGEDAESLDE SATTDMEDDK DPLASGVYDQ SKPGTPLRRV TPLELRRPRS VIAWDHLDRL
PPPPPEPPLS WLAESIEQFE RAAEQRVL
//
