ID A8X8S2_CAEBR Unreviewed; 496 AA.
AC A8X8S2;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063};
DE EC=2.4.1.- {ECO:0000256|RuleBase:RU363063};
GN ORFNames=CBG09575 {ECO:0000313|EMBL:CAP29033.1,
GN ECO:0000313|WormBase:CBG09575}, CBG_09575
GN {ECO:0000313|EMBL:CAP29033.1};
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP29033.1, ECO:0000313|Proteomes:UP000008549};
RN [1] {ECO:0000313|EMBL:CAP29033.1, ECO:0000313|Proteomes:UP000008549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16 {ECO:0000313|EMBL:CAP29033.1,
RC ECO:0000313|Proteomes:UP000008549};
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000256|RuleBase:RU363063}; Single-pass type II membrane protein
CC {ECO:0000256|RuleBase:RU363063}. Membrane
CC {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 31 family.
CC {ECO:0000256|ARBA:ARBA00008661, ECO:0000256|RuleBase:RU363063}.
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DR EMBL; HE600998; CAP29033.1; -; Genomic_DNA.
DR RefSeq; XP_002637076.1; XM_002637030.1.
DR AlphaFoldDB; A8X8S2; -.
DR STRING; 6238.A8X8S2; -.
DR GeneID; 8579072; -.
DR KEGG; cbr:CBG_09575; -.
DR CTD; 8579072; -.
DR WormBase; CBG09575; CBP44912; WBGene00031136; -.
DR eggNOG; KOG2287; Eukaryota.
DR HOGENOM; CLU_550103_0_0_1; -.
DR InParanoid; A8X8S2; -.
DR OrthoDB; 532757at2759; -.
DR Proteomes; UP000008549; Unassembled WGS sequence.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0016758; F:hexosyltransferase activity; IEA:InterPro.
DR GO; GO:0006493; P:protein O-linked glycosylation; IBA:GO_Central.
DR Gene3D; 3.90.550.50; -; 1.
DR InterPro; IPR002619; CX.
DR InterPro; IPR002659; Glyco_trans_31.
DR PANTHER; PTHR11214:SF392; BETA-1,3-GALACTOSYLTRANSFERASE 4; 1.
DR PANTHER; PTHR11214; BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE; 1.
DR Pfam; PF01705; CX; 1.
DR Pfam; PF01762; Galactosyl_T; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|RuleBase:RU363063};
KW Golgi apparatus {ECO:0000256|RuleBase:RU363063};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000008549};
KW Signal {ECO:0000256|SAM:SignalP};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..496
FT /note="Hexosyltransferase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002732803"
FT DOMAIN 120..168
FT /note="CX"
FT /evidence="ECO:0000259|Pfam:PF01705"
FT REGION 21..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 496 AA; 55478 MW; 57EE891C383F71B2 CRC64;
MKLFIFLTLI CSDVIARGGG GRGGGGGGRG GGGARAGVGR GGIGGSGVTG RSVFAGTSRS
GLGGWKTGSS SPASSYGSSS FRSAVFASSY SQSYFTHSSL TNALIISSLA RPITYDNRQY
YWSSSHAKEK LPPDQYPALC EYQIGPDDGQ LQNVSFQDSA PKMSIIFRVN KNEFSDATVF
LNIDRIRTFS TESSLFQVIE TPSHPNWSQN RTYSAQFKDQ RHSYQFVTIP KKQCSNNTKL
QITILSTAGN FEIRQAIRDT WANPNNSKHV ENNDVRISFI ISAAQNEFLN SSIQKEIEKY
DDLIVTDLYE SYELLILKVH AILTYKQNFC ESADFQLKID DDMAVYMEGL YDSLSEKKQS
SVDAISGIIW RNSPPVREKK HRWYVPMTLY SQKHFPPYID GPIYLIGKNV IPKMLDATKN
YSQWIIEDVF WTGILAKALK IRQINWANHL LRYVIELVPS RLKCLNGKPL IYAVHNMKGP
QMIVDGYNKL TGVKCE
//
