ID A8XKZ7_CAEBR Unreviewed; 1407 AA.
AC A8XKZ7;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 2.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=Protein CBR-UNC-40 {ECO:0000313|EMBL:CAP33321.2};
GN Name=unc-40 {ECO:0000313|WormBase:CBG14917a};
GN Synonyms=Cbr-unc-40 {ECO:0000313|EMBL:CAP33321.2};
GN ORFNames=CBG14917 {ECO:0000313|WormBase:CBG14917a}, CBG_14917
GN {ECO:0000313|EMBL:CAP33321.2};
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP33321.2, ECO:0000313|Proteomes:UP000008549};
RN [1] {ECO:0000313|EMBL:CAP33321.2, ECO:0000313|Proteomes:UP000008549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16 {ECO:0000313|EMBL:CAP33321.2,
RC ECO:0000313|Proteomes:UP000008549};
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; HE600904; CAP33321.2; -; Genomic_DNA.
DR STRING; 6238.A8XKZ7; -.
DR WormBase; CBG14917a; CBP45241; WBGene00035291; Cbr-unc-40.
DR eggNOG; KOG4221; Eukaryota.
DR HOGENOM; CLU_004256_2_0_1; -.
DR InParanoid; A8XKZ7; -.
DR OMA; RERMINS; -.
DR OrthoDB; 5398621at2759; -.
DR Proteomes; UP000008549; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd00063; FN3; 6.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 10.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR44170:SF30; FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF00041; fn3; 6.
DR Pfam; PF07679; I-set; 3.
DR Pfam; PF13927; Ig_3; 1.
DR PRINTS; PR00014; FNTYPEIII.
DR SMART; SM00060; FN3; 6.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 4.
DR SUPFAM; SSF49265; Fibronectin type III; 4.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
DR PROSITE; PS50853; FN3; 6.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 4: Predicted;
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008549};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..1407
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002730730"
FT TRANSMEM 1082..1106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 34..127
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 146..233
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 244..330
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 335..420
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 441..531
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 534..629
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 634..729
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 738..829
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 851..944
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 947..1046
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 829..856
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1111..1133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1173..1205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1226..1249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1180..1205
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1407 AA; 153651 MW; 497D26345C930B7A CRC64;
MGCDCYILII LTVYLSTTLA TTRKHHRRST ENDPRSLGFQ FEVEPRRNVT VSESTSHLLE
CSYVLAHERY VQTVRVEWKR DGVMLSERSS SRIKVMSNGS LWIEAMSSAE EGTYQCAVHV
TSKNDLAIDT WTFLSRKATL RLADLSKFEL QPVDRTVAKG QPTAFHCLIN SKPTPSAVWL
HNDQPIVNGG EYHILPVSNT LEISSVQSRH EGTYRCTVEG AGKRRSSQTA RLAVTIGRKV
SNELSFITTP RLQVVEQGGE FLLECLVASR IRPQVRWLKD SRQIIVDGVR IRRVGVSSIL
VSRSSIEDTG LYTCRASNND DSIDRAVSVE VRAPPRITTR PATKVAVETA DVELECGTAA
ARPEARVSWY KNGEAIIGSE YFVIEPSRLR ILGVVRADQA IYQCIAENDV GSEQASAQLL
VDAPDSSSVA ASSGVPMTAS APLGLRSTSS GSRFINVEWD PPVQRNGNIM RYHVFYKDNS
IDRERMINSS STSATLTSLQ PFTMYLIRVT AENEAGMGKF SDSLKVTTNK EQAVPGKVTS
LVATATGPET IDIRWSPPSG GQPALRYKIY YSHDPLEKSE KETLITTSTT HYTLHGMDKY
TGYQIRIEAE GANGSGLSSD TVRIRTQSDE PSAPPVNIQA EADSSTSVRV SWDEPEKYSV
NGEVTGYRLK YKTKARGAKG NTLVIDATSR EYTMGNLEPN TQYLIRMAVV NHNGTGPFSE
WVAVDTPGQD KEERTLGAPR EIRPHAGIDY ILVSWLPPAD EQNLVRGYQI GWGLSVPDTE
TIRVTASTTQ YKISRLSSER DYVISLRAFN NLGSGFPIYE TVRTLSRETP HFSEDSDSDD
ADGQLGSSES TPVGLRTEAV SGTSIRVMWT ESDESAFNTQ YTVRYSTSVD GNQHRYVNST
ETWATVEGLR PATEYEFAVR AVASNGQLST WSMAARNRTW SAPPSSAPRD LTVLPAESGD
PHSASLHWQP PKYSNGEIEE YLVFYTDRES LSDKDWTINY VAGDKLSHQV SNLLPKANYF
FKIQARNEKG HGPFSSIVGY TPSGGAILSG RDRNVPRGHG SAMGDTVSLI EQLQSIFQTN
PLYLMLLIAF ALILILTLIL IIMCCLKRSG GGGRKNGYQS AKKTSGSGGV GGGIGGPPND
LWINGTGSHM RAGASDYMVD GLATAHLTAA DIDSPTPRYH HLQGQGTLTR SYHQSSQSLE
GRQRTPQVVY TGTGRHQPIH KIDFDSPYGS SSAIGSASTP PLPPMQAPPS GPPTVIDGYR
TLRGTPPNSS AANALRSFTQ LAGATPPPPH SATSTSSMRP TIIAAGGRQV PVGRATAQPR
VNVANIYSPF ASCSASSDAG DSDKKGECME MRETTPVKTT GSDKIVANML PSHSTEDLNA
HLESLDTMLD DLQQLQHNLH LDTSTDK
//
