ID   A8XS96_CAEBR            Unreviewed;      2277 AA.
AC   A8XS96;
DT   15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT   16-DEC-2008, sequence version 2.
DT   27-MAR-2024, entry version 73.
DE   SubName: Full=Protein CBG18257 {ECO:0000313|EMBL:CAP35738.2};
GN   Name=dhc-4 {ECO:0000313|WormBase:CBG18257};
GN   ORFNames=CBG18257 {ECO:0000313|EMBL:CAP35738.2,
GN   ECO:0000313|WormBase:CBG18257}, CBG_18257
GN   {ECO:0000313|EMBL:CAP35738.2};
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP35738.2, ECO:0000313|Proteomes:UP000008549};
RN   [1] {ECO:0000313|EMBL:CAP35738.2, ECO:0000313|Proteomes:UP000008549}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16 {ECO:0000313|EMBL:CAP35738.2,
RC   ECO:0000313|Proteomes:UP000008549};
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
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DR   EMBL; HE600936; CAP35738.2; -; Genomic_DNA.
DR   STRING; 6238.A8XS96; -.
DR   WormBase; CBG18257; CBP48326; WBGene00037708; Cbr-dhc-4.
DR   eggNOG; KOG3595; Eukaryota.
DR   HOGENOM; CLU_001231_0_0_1; -.
DR   InParanoid; A8XS96; -.
DR   OMA; CINDHAH; -.
DR   OrthoDB; 2879863at2759; -.
DR   Proteomes; UP000008549; Unassembled WGS sequence.
DR   Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR042222; Dynein_2_N.
DR   InterPro; IPR013602; Dynein_heavy_linker.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR46454:SF17; DHC_N2 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR46454; DYNEIN AXONEMAL HEAVY CHAIN 7-RELATED; 1.
DR   Pfam; PF08393; DHC_N2; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008549}.
FT   DOMAIN          613..1016
FT                   /note="Dynein heavy chain linker"
FT                   /evidence="ECO:0000259|Pfam:PF08393"
FT   REGION          1236..1256
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2277 AA;  264699 MW;  331063F78AF04499 CRC64;
     MPNLLEKEHF KLRKHTRYLT IHRLAEQKSW HQLAYEDRLR RENRKIPKIC RKAFFRWHLE
     QLEARKKFKR LREKNKDESI YVAKQWYYVL KKHPLKPRVE WSFQRVHKLS SKNERIAQEL
     EELMDCAERY ALIDNLSDEF RKKEKYELMK VNSTFWKKCT DKFKVSLLSE IEKFHLEVKN
     SREILLRSQS LAAMKIRIFF EKRKGLIFDI NELIDPEVGN MPIKKLRETI ITKVLEFSQE
     INLKLLRKSW KDEKKRNIVQ NCVVQETTNA AFGTIQLYLK TLRTKTSFIA MDCMIVDRKL
     CVNSEQIRML LKEPISVMCS LENVRMSTED CETWQEEAMM SVDALSHEHI AHHPLLQPYA
     FLVGDYKVSP KLTEEEMIKM YDDSTHLQIR LTKASKCLSV RCFVLRLEAV WVEMERRIRS
     FRNQLKMAIR RKFTTLLNKL LYDFRKYDRA LQYRSIDPSM MLSNKSQVDM MLQNETGDSV
     RQFVDVYDKV FEITQHISLD TSQMDTLLQI ASLRLSLPQC INDHAHFFQK RISTFLHFVN
     KKQAKVMTSV QKAMDKLKIV QTMGNPQEVE TYLAQMMKLR PMLDSLITEI EDLNKFEKAV
     DIQVSDVTKM RHFVGEIESL ESLFVATSGY YKHVNAFFES RRTLVNIDAS RNFIEQFTIQ
     LSIFESSLTT HRAAKHFIAY ARNEVDSFKK NFSVAEVMSC RRLLDAHWLR MSEIVGFDLT
     PYANSSIAQI CELGLEAHLQ QLKPIAFSAE REATAADQLH AIVTFWSQEH LEMRFHSQWK
     LSLAVKLRDL YRRVQNDINT LKHMTNVEQI TDDSLPQWTE WTARAETILK AWCETQQKWM
     RVANIFVTCR DTLQVKNLFN VTQKSEELFT EGIRITENLC QIFPNHREER SKRCDHLSSD
     ATTPFALLDR ENPFNVRGLL DGMRMINARL CLSSELSLLN LFSTTTIDSR LKLLLKDCFP
     SLRRLCFNRR NQLELVDLLG EKITVDLTKA EIENQEPCEL IRSIETAFAS KLTDIITYER
     QDRLKAASRI GANVGELIET RQTLDPLFLS RVIVEYCDEK AYYIQHKSVQ RQSLLTVDFV
     YSIETNRFIP KSLADNWSSG HIILLIGEMC STRNFVLKLS NCLCSNLRIV NSHNLLESAF
     LERLTKCISM TNWFVLLENV DLLTSQLVFN LFKMLSNQAV PFPRLFLSST EEIRNQLPTT
     IAIEHLKDHL GGFHDVIEPS PAFKFDTGTP LSSVRSSSIP NASKLPVGSS LQPPSSPHSV
     LLEKIGARIR NREISGCVGP MAKETLKETL DHFAEKVVWI YIDVFIRDQL VVHSDEFAAS
     PAGILFEVLS PNVLQSNGSE SERSYHSTIS TNSVCINTIV VFYGFSEFWN IFPFISPLFL
     KKDGFSAQTP PFLTLDDGST YWPQENVQFL MCIPDEEGFH LNTVKKFDIP FHVVTENLKM
     DVARSWRKIW QKKYSELFNK ISLVEIMDEL VDRILSPMSS YFSETFLWPS TLFQVIHQDL
     TEVIPLSRTT SVNDTLRITV ILATANYISI FSDDQKKVET KLMKVLVSIR ERLSIQIPDD
     VCNWKISYQD ATKLVKWEEE PFCQSSIDKD SAIGNIMIVT PCMDRLLFYS IRLLSSGHNI
     LVHGPPYSRK TMFVKMISKY LCSSEDANVK FVWLDGKSRV GNDVAQKKFA TIVETCEKAH
     QSEQLYIVID RFSFTEPLLP IIEFFVDHKT YWKDGKLCKS DSQIRMIIVT DEEDYAWLYK
     TKALASTFVG IAMPPSTKFQ DQKPLVQTLI AANFTAKLDL SEKGIILIIN FFFRSFSSEY
     HHHLEPLSSC IVEIVKKPYV KNLSSMALAT RLAKSFFFAF PDNCPDPNAL LRLFIHESAR
     VIGDAIDPSH RPTFARQFET LIDENFNTTQ QAILKHIAQI SDNEEDEEEK EGIEKRPPTT
     IDMFDLIYSE VDAHDVVDGL SYEPVVDRVQ FQRSIENFLF EHHRNHPKDR IRLFIDWETS
     GWVQRVMRVI RQASEHMVLV APPNSGRTQV VKAACVACNA TMMHMQVDAT CYDTFISRWE
     YALSRAINII ANTNQHVVIL VHLDFCYEKV EPRWMEQIKL WIECPNTQHL VSDEQLHTMG
     EQLIECEKNL ATQMQTIGLR LPGQRMCKYL PVETLKEPQA LRKVLEARIF DALHVMFLVD
     PQFKSDFSWC TIFHVPVSFF FVRSLLKHWK IQNIEKSDLI SKVSKIISDC KVDEATQIIV
     STFFIGSFSR DFSRFLNESL SVKKYLQAIG IALPGTLFSQ LFEVADCFQI VFRQQKK
//