ID A8XVN8_CAEBR Unreviewed; 1012 AA.
AC A8XVN8;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Protein CBR-ADR-1 {ECO:0000313|EMBL:CAP36691.1};
GN Name=adr-1 {ECO:0000313|WormBase:CBG19440a};
GN Synonyms=Cbr-adr-1 {ECO:0000313|EMBL:CAP36691.1};
GN ORFNames=CBG19440 {ECO:0000313|WormBase:CBG19440a}, CBG_19440
GN {ECO:0000313|EMBL:CAP36691.1};
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP36691.1, ECO:0000313|Proteomes:UP000008549};
RN [1] {ECO:0000313|EMBL:CAP36691.1, ECO:0000313|Proteomes:UP000008549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16 {ECO:0000313|EMBL:CAP36691.1,
RC ECO:0000313|Proteomes:UP000008549};
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
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DR EMBL; HE601126; CAP36691.1; -; Genomic_DNA.
DR RefSeq; XP_002646471.1; XM_002646425.1.
DR AlphaFoldDB; A8XVN8; -.
DR STRING; 6238.A8XVN8; -.
DR GeneID; 8588468; -.
DR KEGG; cbr:CBG_19440; -.
DR CTD; 8588468; -.
DR WormBase; CBG19440a; CBP39236; WBGene00038662; Cbr-adr-1.
DR eggNOG; KOG2777; Eukaryota.
DR HOGENOM; CLU_327701_0_0_1; -.
DR InParanoid; A8XVN8; -.
DR OMA; NALEMIS; -.
DR OrthoDB; 118472at2759; -.
DR Proteomes; UP000008549; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0003726; F:double-stranded RNA adenosine deaminase activity; IBA:GO_Central.
DR GO; GO:0003725; F:double-stranded RNA binding; IBA:GO_Central.
DR GO; GO:0008251; F:tRNA-specific adenosine deaminase activity; IBA:GO_Central.
DR GO; GO:0006382; P:adenosine to inosine editing; IBA:GO_Central.
DR GO; GO:0006396; P:RNA processing; IBA:GO_Central.
DR CDD; cd00048; DSRM_SF; 2.
DR Gene3D; 3.30.160.20; -; 2.
DR InterPro; IPR002466; A_deamin.
DR InterPro; IPR014720; dsRBD_dom.
DR PANTHER; PTHR10910:SF144; A TO I EDITASE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR10910; EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN; 1.
DR Pfam; PF02137; A_deamin; 1.
DR Pfam; PF00035; dsrm; 2.
DR SMART; SM00552; ADEAMc; 1.
DR SMART; SM00358; DSRM; 2.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 2.
DR PROSITE; PS50141; A_DEAMIN_EDITASE; 1.
DR PROSITE; PS50137; DS_RBD; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008549};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00266}.
FT DOMAIN 210..272
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 570..645
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 712..1000
FT /note="A to I editase"
FT /evidence="ECO:0000259|PROSITE:PS50141"
FT REGION 1..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 81..124
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 167..210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 277..323
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 377..407
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 81..106
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 184..199
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 299..317
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1012 AA; 111758 MW; 2F1126A27014BE96 CRC64;
MDPNLNFNYP YSDNYSGSGA ATGDTNDSSQ QFGWASQWTQ PASATSQGAG GYPQYVSQHQ
QQAQQQAQQA YAMMNPLSPF MQSQQKPQQQ QLQLQQQFQQ QKKFGQHGPV GTPKAPGSQL
GGAFNPRAFG AFGAVGGGGD RSTSSGGILG QEWTGEAANQ FGMQSHLRTF PSKSGGGPGG
HSKPNWRQQK QQRQSAGPPA PKKTETAGKT PAMILHEVFK SITEDYSEVE GAVPKRYICT
LTVNGRQFQM ESANKKAAKQ KCAEAVVREL RPDLHVTPFE EGVTAKATPP APPKSAAGNG
QPNKRNAEDQ TNQPAAKKTA APGAVKKIKL TPVESAQSLL DFMQKTIAES KEKYTPVFEA
IELPRAEEMV EVKAEDMKQE PTEVTVDENA EAPAAGAKRS KKEKVRKPEV QHQVTLKFLE
QGKEFTKTGP NRGMLKDMLI REALREVFNV PQEAITIVAR RHALNRLGTD MNLVQCLQTI
AGVLNCKVSL DTEPAEDRPI GDGKMYFMGR AKIIDLNEDG KEFETKSTSV PSKALAREHA
AMEMLKQYFK MDTDSIQTNE AHGNSSGQQG PCAVLHAMMN KATKQQTKIG YEFKDNVPPV
AGAGSPGPVF YCDCVIDEER FTGSGRSKKL AKNAAAVVAL KRKFSVDYNP DGMCPLAHSS
RPERQCSPLC REISEFCKRE YYDMTRHYGV NQSNQIACFV LINDRNEKRI LSIGSSIQYV
CEPDSLNGAD GNHIVHMDPI VLARRGLIRS IYHELLYMPP EGSVVFEKQP DGRYALNKTM
KLVLYSNFSP ACRFSCDDVP KKSLSYVTPL TCKPVPEDVL TLDEIREKRE IRIHSTADKL
FKWNHLGVQG ALLSHVLHPL FISHIFFGTQ APVPDDSLKF ALVNRIGPVD AGADHQETEL
ESVQGNMEVF TTRYSHVWSR GLDLIEQLDV STGRTINGMP SSVCKAQLFA NYCQLPHVTQ
KDVNYGKEKE ASSNYQYEKK VLYEKLEAAG LGKWQTKPME LVDSFTLPAS FN
//
