ID A8XXJ0_CAEBR Unreviewed; 471 AA.
AC A8XXJ0;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE SubName: Full=Protein CBR-CEH-81 {ECO:0000313|EMBL:CAP37359.1};
GN Name=ceh-81 {ECO:0000313|WormBase:CBG20316};
GN Synonyms=Cbr-ceh-81 {ECO:0000313|EMBL:CAP37359.1};
GN ORFNames=CBG20316 {ECO:0000313|WormBase:CBG20316}, CBG_20316
GN {ECO:0000313|EMBL:CAP37359.1};
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP37359.1, ECO:0000313|Proteomes:UP000008549};
RN [1] {ECO:0000313|EMBL:CAP37359.1, ECO:0000313|Proteomes:UP000008549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16 {ECO:0000313|EMBL:CAP37359.1,
RC ECO:0000313|Proteomes:UP000008549};
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
CC ECO:0000256|RuleBase:RU000682}.
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DR EMBL; HE601445; CAP37359.1; -; Genomic_DNA.
DR RefSeq; XP_002647746.1; XM_002647700.1.
DR AlphaFoldDB; A8XXJ0; -.
DR STRING; 6238.A8XXJ0; -.
DR EnsemblMetazoa; CBG20316.1; CBG20316.1; WBGene00039330.
DR GeneID; 8589744; -.
DR KEGG; cbr:CBG_20316; -.
DR CTD; 8589744; -.
DR WormBase; CBG20316; CBP24037; WBGene00039330; Cbr-ceh-81.
DR eggNOG; ENOG502RT8A; Eukaryota.
DR HOGENOM; CLU_580362_0_0_1; -.
DR InParanoid; A8XXJ0; -.
DR OMA; ENERMLM; -.
DR Proteomes; UP000008549; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd00086; homeodomain; 2.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR PANTHER; PTHR24327:SF41; BRAIN-SPECIFIC HOMEOBOX PROTEIN; 1.
DR PANTHER; PTHR24327; HOMEOBOX PROTEIN; 1.
DR Pfam; PF00046; Homeodomain; 2.
DR SMART; SM00389; HOX; 2.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR PROSITE; PS50071; HOMEOBOX_2; 2.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000008549}.
FT DOMAIN 28..88
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DOMAIN 106..166
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 30..89
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT DNA_BIND 108..167
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 169..459
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 173..217
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 230..303
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 304..326
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 337..368
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 375..398
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 435..449
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 471 AA; 54003 MW; 7330171A1AE8A3A9 CRC64;
MPTPRQSGIT KKEALAIIQR CKARVAASSR RAQGTRFTEF QYSVLQARFA VKPAPKAREQ
SALSQAIGMT PKQVEDWFKH TSKKASKFKK TKDKAVLKIL KDAKKEIGRF PNTHLSLKNR
AVLCAWFEIH NKISAPEQVE LAKELGIRSL SIQYWFNSRR KKIRNGRGVE EAVYDDDDPE
EDEDPQDQEN QADLEDQEDQ DQDEQVQADL EEPEDQDSTD SKADHDDEGR QEENLEEIPE
DQEEQDPMED AEDELEDPED QEEQDPMEDT EDELEDPEDQ EEKDPMEEED PADLEEPDAQ
NPMDSEDDES RQAENLHELP EHQEDQEPME ELADSNGQEL DFQSLVENGG AEDQKQNLPE
NQDVVNREML QNPEDLEEPD AVEDASEDPE DPEEPVVDAD APEGPAPDQA PDFHINQWPE
EDQDAQFGRQ APDNEDGMAA DRPGRFREGR ELPQGLNQHQ IDYQNDLFMD F
//
