ID A9AA11_METM6 Unreviewed; 639 AA.
AC A9AA11;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=MmarC6_1371 {ECO:0000313|EMBL:ABX02184.1};
OS Methanococcus maripaludis (strain C6 / ATCC BAA-1332).
OC Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC Methanococcaceae; Methanococcus.
OX NCBI_TaxID=444158 {ECO:0000313|EMBL:ABX02184.1};
RN [1] {ECO:0000313|EMBL:ABX02184.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C6 {ECO:0000313|EMBL:ABX02184.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Clum A., Schmutz J., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Mikhailova N., Sieprawska-Lupa M., Whitman W.B.,
RA Richardson P.;
RT "Complete sequence of Methanococcus maripaludis C6.";
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP000867; ABX02184.1; -; Genomic_DNA.
DR AlphaFoldDB; A9AA11; -.
DR STRING; 444158.MmarC6_1371; -.
DR KEGG; mmx:MmarC6_1371; -.
DR eggNOG; arCOG02320; Archaea.
DR HOGENOM; CLU_000445_89_6_2; -.
DR OrthoDB; 342253at2157; -.
DR PhylomeDB; A9AA11; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd18773; PDC1_HK_sensor; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR033463; sCache_3.
DR InterPro; IPR029151; Sensor-like_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43711:SF1; HISTIDINE KINASE 1; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF17202; sCache_3_3; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ABX02184.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ABX02184.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 14..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 318..336
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 338..390
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 419..636
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 639 AA; 70848 MW; B31C88C71AE1B344 CRC64;
MNTIPPIKRL GTKLIIYSII TALIPIVMLG AVSTDTINTE MTKQAQEKIN DDLNTAESVV
TLKLDKISAM NKYIVSNENT IDGLKKGNTL ELKNIALSYK DASDPDFVVF FDSTGHVIAR
SNSDVIGDKA YENLFNKLLN GTGYTSMEVL DRESIQYENV DELVNIDIKG TEDSIDSTDS
VQDSAMALIS IEPIYNVDGT LLGAAMAADI LNKDYSIVDT VKDASKDATT IFLDGVRIST
NVQDNGGRAI GTLVSEEVYK YVVLDGNTYY GRAFVVNEWY LTAYEPIYDS DGKIIGMLFV
GTPESKFLAL QAYVRNQTFA VGLIGLFIAL IASYIINRGI IKPLEQLKQG AERVSNGRYD
QKVVVDSDDE FGELAKAFNK MATQINISDE KLKKHAEELK ASYNELKELD NLKSELIAIV
SHELRTPLTS IKGYVELVLD GTMGAINDSQ KKCLQVADDN IVRLRRLIES MLDLSKIERG
ELEMYREKVN LKGIVCDVIE YLQPIATEKN IKLKKEIEEI AIDADKDRIT QVLTNLIENA
IKFSPANESI MISADLEDEH VHLRVTDHGA GIPKKDMEKV FNRFYQVDSS TKRKKGGSGL
GLAVCKSIVE AHKGSIWVES ELGKGSTFHI ILPLSIEDM
//
