ID A9CIU4_AGRFC Unreviewed; 518 AA.
AC A9CIU4;
DT 15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE RecName: Full=Phospholipase D {ECO:0000256|ARBA:ARBA00018392};
DE AltName: Full=Choline phosphatase {ECO:0000256|ARBA:ARBA00029594};
GN OrderedLocusNames=Atu1630 {ECO:0000313|EMBL:AAK87408.1};
OS Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens
OS (strain C58)).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium;
OC Agrobacterium tumefaciens complex.
OX NCBI_TaxID=176299 {ECO:0000313|EMBL:AAK87408.1, ECO:0000313|Proteomes:UP000000813};
RN [1] {ECO:0000313|EMBL:AAK87408.1, ECO:0000313|Proteomes:UP000000813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C58 / ATCC 33970 {ECO:0000313|Proteomes:UP000000813};
RX PubMed=11743193; DOI=10.1126/science.1066804;
RA Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K.,
RA Zhou Y., Chen L., Wood G.E., Almeida N.F.Jr., Woo L., Chen Y.,
RA Paulsen I.T., Eisen J.A., Karp P.D., Bovee D.Sr., Chapman P.,
RA Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R.,
RA Li M.J., McClelland E., Palmieri A., Raymond C., Rouse G.,
RA Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y.,
RA Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S.,
RA Hendrick C., Zhao Z.Y., Dolan M., Chumley F., Tingey S.V., Tomb J.F.,
RA Gordon M.P., Olson M.V., Nester E.W.;
RT "The genome of the natural genetic engineer Agrobacterium tumefaciens
RT C58.";
RL Science 294:2317-2323(2001).
RN [2] {ECO:0000313|EMBL:AAK87408.1, ECO:0000313|Proteomes:UP000000813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C58 / ATCC 33970 {ECO:0000313|Proteomes:UP000000813};
RX PubMed=11743194; DOI=10.1126/science.1066803;
RA Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B.,
RA Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K.,
RA Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M.,
RA Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C.,
RA Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
RT "Genome sequence of the plant pathogen and biotechnology agent
RT Agrobacterium tumefaciens C58.";
RL Science 294:2323-2328(2001).
CC -!- FUNCTION: Could be a virulence factor. {ECO:0000256|ARBA:ARBA00003145}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR EMBL; AE007869; AAK87408.1; -; Genomic_DNA.
DR PIR; AB2777; AB2777.
DR PIR; G97556; G97556.
DR RefSeq; NP_354623.1; NC_003062.2.
DR RefSeq; WP_010971756.1; NC_003062.2.
DR AlphaFoldDB; A9CIU4; -.
DR STRING; 176299.Atu1630; -.
DR EnsemblBacteria; AAK87408; AAK87408; Atu1630.
DR KEGG; atu:Atu1630; -.
DR PATRIC; fig|176299.10.peg.1651; -.
DR eggNOG; COG1502; Bacteria.
DR HOGENOM; CLU_026287_0_0_5; -.
DR OrthoDB; 9814092at2; -.
DR PhylomeDB; A9CIU4; -.
DR BioCyc; AGRO:ATU1630-MONOMER; -.
DR Proteomes; UP000000813; Chromosome circular.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030572; F:phosphatidyltransferase activity; IEA:UniProt.
DR GO; GO:0032049; P:cardiolipin biosynthetic process; IEA:UniProt.
DR CDD; cd09111; PLDc_ymdC_like_1; 1.
DR CDD; cd09113; PLDc_ymdC_like_2; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR InterPro; IPR025202; PLD-like_dom.
DR InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR PANTHER; PTHR21248; CARDIOLIPIN SYNTHASE; 1.
DR PANTHER; PTHR21248:SF12; CARDIOLIPIN SYNTHASE C; 1.
DR Pfam; PF13091; PLDc_2; 2.
DR SMART; SM00155; PLDc; 2.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR PROSITE; PS50035; PLD; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000813};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 172..199
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
FT DOMAIN 408..435
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
SQ SEQUENCE 518 AA; 58096 MW; F08804A62B810AE2 CRC64;
MTAFTVFIII LLMLIGPSLF VVIGKQREKA IPKRPSTALP VTEDETALDR HWQSIRNGWN
EKNALCLLHS NLDAFAVRVA AARAAGRSLD LMYYMWNADL TGRLMMREVI AAADRGVRVR
LLLDDLGVSM SDRIFHAIDS HPNIELRLFN PTRARENILH RSLELVLRFR SVNRRMHNKA
WIADGRAVIV GGRNIGDAYF DAAERANFHD FDILGFGGIV ADATEIFDDY WNSAVSVPVR
SLLARRPNKL AKLRRELDAL PQSEAARPYL ERVESQYGRD HFLMSDRLHW VDTADVLADP
PEKAAGKRRK GHNFLMESLL PLMQAAGESL HITSPYFIPG KQGVEIFLDL AERGVSLAIL
TNSLAATDVA AVHAGYARYR KPLLSGGVRL HELRSQADQG SFTLRGSGQA SLHTKAFTRD
GETGYIGSLN FDPRSASLNT EMGVVFNSAP LVARMDEIFA EEIRRTMSFE LDIDSANRIV
WMTEERGQPK IYRREPDAAI SRRIIAGIMR VLPLESQL
//
