ID A9DCP3_9GAMM Unreviewed; 250 AA.
AC A9DCP3;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 24-JAN-2024, entry version 71.
DE RecName: Full=Pyruvate dehydrogenase complex repressor {ECO:0000256|ARBA:ARBA00039592};
GN Name=pdhR {ECO:0000313|EMBL:EDQ00249.1};
GN ORFNames=KT99_07478 {ECO:0000313|EMBL:EDQ00249.1};
OS Shewanella benthica KT99.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Shewanellaceae; Shewanella.
OX NCBI_TaxID=314608 {ECO:0000313|EMBL:EDQ00249.1, ECO:0000313|Proteomes:UP000005839};
RN [1] {ECO:0000313|EMBL:EDQ00249.1, ECO:0000313|Proteomes:UP000005839}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KT99 {ECO:0000313|EMBL:EDQ00249.1,
RC ECO:0000313|Proteomes:UP000005839};
RA Yayanos A., Ferriera S., Johnson J., Kravitz S., Halpern A., Remington K.,
RA Beeson K., Tran B., Rogers Y.-H., Friedman R., Venter J.C.;
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Transcriptional repressor for the pyruvate dehydrogenase
CC complex genes aceEF and lpd. {ECO:0000256|ARBA:ARBA00037357}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDQ00249.1}.
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DR EMBL; ABIC01000023; EDQ00249.1; -; Genomic_DNA.
DR RefSeq; WP_005500227.1; NZ_ABIC01000023.1.
DR AlphaFoldDB; A9DCP3; -.
DR STRING; 314608.KT99_07478; -.
DR Proteomes; UP000005839; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 1.20.120.530; GntR ligand-binding domain-like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011711; GntR_C.
DR InterPro; IPR008920; TF_FadR/GntR_C.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43537:SF34; PYRUVATE DEHYDROGENASE COMPLEX REPRESSOR; 1.
DR PANTHER; PTHR43537; TRANSCRIPTIONAL REGULATOR, GNTR FAMILY; 1.
DR Pfam; PF07729; FCD; 1.
DR Pfam; PF00392; GntR; 1.
DR PRINTS; PR00035; HTHGNTR.
DR SMART; SM00895; FCD; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF48008; GntR ligand-binding domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyruvate {ECO:0000313|EMBL:EDQ00249.1};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 9..77
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 250 AA; 28435 MW; BE97F45E31CA0C40 CRC64;
MAYNKINQPK ISDVIMGQLE QMILEGSLQP GQKLPPEREL ALQFEVSRPS LREAIQKLEA
KGLLLRRQGG GTYVKEQLWQ SLADPIVELM HSDPESQYDL LEFRHATEGM MAYFAALRGT
DADMQHIKRT IMDVEAAQEI EQQAEAIVHF YRAIAEASHN VAMLHLVLSL APVLHKNVAQ
NLELLNRREE ASTRANEHRL ALLAAIVRRD PDAAREASNE HLSYIEEVML TVRKEDSRLQ
RSLRRLKSGN
//
