ID A9GB34_SORC5 Unreviewed; 787 AA.
AC A9GB34;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 24-JAN-2024, entry version 87.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=sce2791 {ECO:0000313|EMBL:CAN92950.1};
OS Sorangium cellulosum (strain So ce56) (Polyangium cellulosum (strain So
OS ce56)).
OC Bacteria; Myxococcota; Polyangia; Polyangiales; Polyangiaceae; Sorangium.
OX NCBI_TaxID=448385 {ECO:0000313|EMBL:CAN92950.1, ECO:0000313|Proteomes:UP000002139};
RN [1] {ECO:0000313|EMBL:CAN92950.1, ECO:0000313|Proteomes:UP000002139}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=So ce56 {ECO:0000313|Proteomes:UP000002139};
RX PubMed=17965706; DOI=10.1038/nbt1354;
RA Schneiker S., Perlova O., Kaiser O., Gerth K., Alici A., Altmeyer M.O.,
RA Bartels D., Bekel T., Beyer S., Bode E., Bode H.B., Bolten C.J.,
RA Choudhuri J.V., Doss S., Elnakady Y.A., Frank B., Gaigalat L., Goesmann A.,
RA Groeger C., Gross F., Jelsbak L., Jelsbak L., Kalinowski J., Kegler C.,
RA Knauber T., Konietzny S., Kopp M., Krause L., Krug D., Linke B., Mahmud T.,
RA Martinez-Arias R., McHardy A.C., Merai M., Meyer F., Mormann S.,
RA Munoz-Dorado J., Perez J., Pradella S., Rachid S., Raddatz G., Rosenau F.,
RA Rueckert C., Sasse F., Scharfe M., Schuster S.C., Suen G.,
RA Treuner-Lange A., Velicer G.J., Vorholter F.-J., Weissman K.J., Welch R.D.,
RA Wenzel S.C., Whitworth D.E., Wilhelm S., Wittmann C., Bloecker H.,
RA Puehler A., Mueller R.;
RT "Complete genome sequence of the myxobacterium Sorangium cellulosum.";
RL Nat. Biotechnol. 25:1281-1289(2007).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; AM746676; CAN92950.1; -; Genomic_DNA.
DR RefSeq; WP_012235423.1; NC_010162.1.
DR AlphaFoldDB; A9GB34; -.
DR STRING; 448385.sce2791; -.
DR KEGG; scl:sce2791; -.
DR eggNOG; COG2205; Bacteria.
DR HOGENOM; CLU_357841_0_0_7; -.
DR OrthoDB; 5500479at2; -.
DR BioCyc; SCEL448385:SCE_RS14315-MONOMER; -.
DR Proteomes; UP000002139; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004673; F:protein histidine kinase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR45569; SENSOR PROTEIN KDPD; 1.
DR PANTHER; PTHR45569:SF1; SENSOR PROTEIN KDPD; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:CAN92950.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002139};
KW Transferase {ECO:0000313|EMBL:CAN92950.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 129..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..177
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 189..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 220..242
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 347..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 378..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 579..777
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 462..491
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 787 AA; 85165 MW; C7E7739E4FE4D86D CRC64;
MPAIENRRWL LAVVVLAALV LGGSGMRSAL SWYERPFPGV LVDPDGVVSS VGLPSWEGFQ
KGLRYPDRVV EVDGWHLEST EGRYRAGAWD AAVERAAREG RRSVHARVET AEGLRDVELS
LVPFDALAWW FYAGGLMVVA SLYVGAALIA LSASPHGKLA RAFASAALFA ALFQFALFDY
HSSRHLVPFF HVAYALVPMS FFTLALRLPD DVPLIARYPV FARIAHGLGG LLAAALLASH
AMGWTTVALR SVCAILFVAS FFFFATTLIL RFAAAEGDRR RTLRALLLAM APPHVVIALG
FMLAMLGAPA STLAWFAIPA LALTPVSSVV AFIRYDLWGS RALLSRPLTR VIIACMMVAL
TVILCSACAG YAGLPLLGAI KVAAPAAVVS AALVVFALGA GDRKLFPARA EYKPTVEQLS
EELTLVADPD EVAFAVERTV ARWLSCERVT FRRIAVDAAD GAGAGSAGAA PGEPASRADE
SSGERVIEVE PSKASASASE LSLTVMFRGR LLGVLEVGKK RGGALFTSED LDLLRTIGNQ
AALAMAHAHS YAELERRRRE QAAAWRDERA ALIETLAAEI THEVRYPINF FRSVFKRGSK
NQSLDAEEVD IGCEEVERLE RLVMGLRRVT HRKLERRRLA VEELVSRAEM LLRDQLGKRR
IEARVSAGSR LRCDPDQATQ VLVNLLSNGL DAAGDKGTIG VVWETTESGA ELVVWDTGPG
ISGDASRLFA PWYTTKPRGT GLGLAITHRI VRAHGWLIEP ERRDGTTRFV ISIPAADVSM
TAEDEVA
//
