ID   A9NUZ3_PICSI            Unreviewed;       539 AA.
AC   A9NUZ3;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 1.
DT   22-FEB-2023, entry version 52.
DE   RecName: Full=FYVE-type domain-containing protein {ECO:0000259|PROSITE:PS50178};
OS   Picea sitchensis (Sitka spruce) (Pinus sitchensis).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Pinopsida; Pinidae; Conifers I; Pinales; Pinaceae; Picea.
OX   NCBI_TaxID=3332 {ECO:0000313|EMBL:ABK24454.1};
RN   [1] {ECO:0000313|EMBL:ABK24454.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Bark {ECO:0000313|EMBL:ABK24454.1};
RX   PubMed=18854048; DOI=10.1186/1471-2164-9-484;
RA   Ralph S.G., Chun H.J., Kolosova N., Cooper D., Oddy C., Ritland C.E.,
RA   Kirkpatrick R., Moore R., Barber S., Holt R.A., Jones S.J., Marra M.A.,
RA   Douglas C.J., Ritland K., Bohlmann J.;
RT   "A conifer genomics resource of 200,000 spruce (Picea spp.) ESTs and 6,464
RT   high-quality, sequence-finished full-length cDNAs for Sitka spruce (Picea
RT   sitchensis).";
RL   BMC Genomics 9:484-484(2008).
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DR   EMBL; EF085147; ABK24454.1; -; mRNA.
DR   AlphaFoldDB; A9NUZ3; -.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR   GO; GO:0036258; P:multivesicular body assembly; IEA:InterPro.
DR   CDD; cd15730; FYVE_EEA1; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR045893; FREE1.
DR   InterPro; IPR000306; Znf_FYVE.
DR   InterPro; IPR017455; Znf_FYVE-rel.
DR   InterPro; IPR011011; Znf_FYVE_PHD.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR46977; PROTEIN FREE1; 1.
DR   PANTHER; PTHR46977:SF1; PROTEIN FREE1; 1.
DR   Pfam; PF01363; FYVE; 1.
DR   SMART; SM00064; FYVE; 1.
DR   SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR   PROSITE; PS50178; ZF_FYVE; 1.
PE   2: Evidence at transcript level;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00091}.
FT   DOMAIN          380..440
FT                   /note="FYVE-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50178"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          471..499
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        8..24
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        476..497
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   539 AA;  58669 MW;  2A783E415989FAE8 CRC64;
     MHYPGSSYYP TEQPNSNNPS YNWASAPPYG EAAAPAYYPP APEPVVAPTH GSDPSNYSYN
     LPQTIPASYP NPFPQYAPPN ASQFTPQSPI ISPPPPATNA NYLYSSNPTA PVYHSAAAAQ
     NPAYDQGFAY PDHRGYENRD SFQYPGFDQK YYETPVGKDP GYDRSGFDVD DGGFGGEVYA
     YDGGRGEPYG ARGTGTVSGT GAGSKPLAAF DDYGNLTKIT KAVPKAETQD GGNGVQKFRV
     KILPDSGSQN TLDVLCQIGL DGLRMLDPST NRTLRIYPLE TITKWEVTDP SVYTFWAKSS
     VDLDPRRIRL QSNRYTTNTI LDTVAAACVQ LREMVDDKSS GNNSDTSKAS DQLTEKRRSS
     LADWVTLKKP VEEKQHWVPD EAVTSCKGCG TDFGAFVRRH HCRNCGDIFC DKCTQGRAAL
     TADKDAQPVR VCDRCLAEVT QRLTSTKETS SKATAQRSHD DLAKRLMEEM GRNRKGNSDS
     GSGSSPLWSS QSISDGTGKR MRDVACPTCT VHLQVQVPSS GTETVECGVC QHPFLVSAR
//