ID A9T788_PHYPA Unreviewed; 743 AA.
AC A9T788;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE RecName: Full=Cullin family profile domain-containing protein {ECO:0000259|PROSITE:PS50069};
GN ORFNames=PHYPA_008885 {ECO:0000313|EMBL:PNR52511.1};
OS Physcomitrium patens (Spreading-leaved earth moss) (Physcomitrella patens).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Bryophyta;
OC Bryophytina; Bryopsida; Funariidae; Funariales; Funariaceae; Physcomitrium.
OX NCBI_TaxID=3218 {ECO:0000313|EMBL:PNR52511.1};
RN [1] {ECO:0000313|EMBL:PNR52511.1, ECO:0000313|Proteomes:UP000006727}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Gransden 2004 {ECO:0000313|EnsemblPlants:Pp3c6_12900V3.1,
RC ECO:0000313|Proteomes:UP000006727};
RX PubMed=18079367; DOI=10.1126/science.1150646;
RA Rensing S.A., Lang D., Zimmer A.D., Terry A., Salamov A., Shapiro H.,
RA Nishiyama T., Perroud P.-F., Lindquist E.A., Kamisugi Y., Tanahashi T.,
RA Sakakibara K., Fujita T., Oishi K., Shin-I T., Kuroki Y., Toyoda A.,
RA Suzuki Y., Hashimoto S.-I., Yamaguchi K., Sugano S., Kohara Y.,
RA Fujiyama A., Anterola A., Aoki S., Ashton N., Barbazuk W.B., Barker E.,
RA Bennetzen J.L., Blankenship R., Cho S.H., Dutcher S.K., Estelle M.,
RA Fawcett J.A., Gundlach H., Hanada K., Heyl A., Hicks K.A., Hughes J.,
RA Lohr M., Mayer K., Melkozernov A., Murata T., Nelson D.R., Pils B.,
RA Prigge M., Reiss B., Renner T., Rombauts S., Rushton P.J., Sanderfoot A.,
RA Schween G., Shiu S.-H., Stueber K., Theodoulou F.L., Tu H., Van de Peer Y.,
RA Verrier P.J., Waters E., Wood A., Yang L., Cove D., Cuming A.C., Hasebe M.,
RA Lucas S., Mishler B.D., Reski R., Grigoriev I.V., Quatrano R.S.,
RA Boore J.L.;
RT "The Physcomitrella genome reveals evolutionary insights into the conquest
RT of land by plants.";
RL Science 319:64-69(2008).
RN [2] {ECO:0000313|EMBL:PNR52511.1, ECO:0000313|Proteomes:UP000006727}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Gransden 2004 {ECO:0000313|EnsemblPlants:Pp3c6_12900V3.1,
RC ECO:0000313|Proteomes:UP000006727};
RX PubMed=29237241; DOI=10.1111/tpj.13801;
RA Lang D., Ullrich K.K., Murat F., Fuchs J., Jenkins J., Haas F.B.,
RA Piednoel M., Gundlach H., Van Bel M., Meyberg R., Vives C., Morata J.,
RA Symeonidi A., Hiss M., Muchero W., Kamisugi Y., Saleh O., Blanc G.,
RA Decker E.L., van Gessel N., Grimwood J., Hayes R.D., Graham S.W.,
RA Gunter L.E., McDaniel S.F., Hoernstein S.N.W., Larsson A., Li F.W.,
RA Perroud P.F., Phillips J., Ranjan P., Rokshar D.S., Rothfels C.J.,
RA Schneider L., Shu S., Stevenson D.W., Thummler F., Tillich M.,
RA Villarreal Aguilar J.C., Widiez T., Wong G.K., Wymore A., Zhang Y.,
RA Zimmer A.D., Quatrano R.S., Mayer K.F.X., Goodstein D., Casacuberta J.M.,
RA Vandepoele K., Reski R., Cuming A.C., Tuskan G.A., Maumus F., Salse J.,
RA Schmutz J., Rensing S.A.;
RT "The Physcomitrella patens chromosome-scale assembly reveals moss genome
RT structure and evolution.";
RL Plant J. 93:515-533(2018).
RN [3] {ECO:0000313|EnsemblPlants:Pp3c6_12900V3.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (DEC-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the cullin family.
CC {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC ECO:0000256|RuleBase:RU003829}.
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DR EMBL; ABEU02000006; PNR52511.1; -; Genomic_DNA.
DR RefSeq; XP_001774461.1; XM_001774409.1.
DR AlphaFoldDB; A9T788; -.
DR STRING; 3218.A9T788; -.
DR PaxDb; 3218-PP1S177_52V6-1; -.
DR EnsemblPlants; Pp3c6_12900V3.1; Pp3c6_12900V3.1; Pp3c6_12900.
DR EnsemblPlants; Pp3c6_12900V3.3; Pp3c6_12900V3.3; Pp3c6_12900.
DR Gramene; Pp3c6_12900V3.1; Pp3c6_12900V3.1; Pp3c6_12900.
DR Gramene; Pp3c6_12900V3.3; Pp3c6_12900V3.3; Pp3c6_12900.
DR eggNOG; KOG2166; Eukaryota.
DR HOGENOM; CLU_004747_3_0_1; -.
DR InParanoid; A9T788; -.
DR OMA; DSFKERM; -.
DR OrthoDB; 21270at2759; -.
DR Proteomes; UP000006727; Chromosome 6.
DR GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IBA:GO_Central.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IBA:GO_Central.
DR GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; CULLIN; 1.
DR PANTHER; PTHR11932:SF126; CULLIN 4, ISOFORM A; 1.
DR Pfam; PF00888; Cullin; 1.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR SMART; SM00182; CULLIN; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006727}.
FT DOMAIN 388..618
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
SQ SEQUENCE 743 AA; 86717 MW; 1E232EEFCC7C40A1 CRC64;
MINERRVIEL EQGWNFMQKG ITKLKNLLEG VPEQQFSSEE YMLLYTTIYN MCTQKPPQDY
SQQLYDRYRE SFEGYINSKV LPALREKHEE FMLKELVKRW DNHKIMVRWL SRFFNYLDRY
FIARRSLPAL SEVGLMRFRD LVYEEMKVNV KDAVIALIDR EREGEQIDRA LLKNVLGIFV
EIGMGNMDAY ETDFEAFMLE DTASYYKRKA SSWIQEDSCP DYMLKAEECL KRERERVGHY
LHASSEQKLL EKVQHELLTQ YETQLLEKEH SGCHTLLRDD KVDDLSRMYR LFCRILKGLD
PVAAIFREHV TGEGTALVKQ AEDAASNKKA ERKDIVGVQE QAFVRKVIEL HDKYLQYVSD
CFLNHSLFHK ALKEAFEVFC NKGVAGSTSA ELLATFCDNL LKKGGSEKLS DEAIEDTLEK
VVKLLAYISD KDLFAEFYRK KLARRLLFDK SANDDHERSI LTKLKQQCGG QFTSKMEGMV
TDLTLARENQ INFEEYLSDN TQSNPGIDLT VTVLTTGFWP SYKSSDLALP AEMVKCVEVF
KEFYQTKTKH RKLTWIYSLG TCNITGKFDA KPIELIVTTY QAAVLLLFNA ADRLSYNDIK
SQLNLTDEDI VRLLHSLSCA KYKILNKDPI TKTVGQSDIF EFNTKFTDKM RRIKIPLPPM
DEKKKVIEDV DKDRRYAIDA SIVRIMKSRK MLPHQQLVLE CVEQLGRMFK PDFKVIKKRV
EDLIAREYLE RDKDNPNVFK YVA
//
