ID A9UTB3_MONBE Unreviewed; 321 AA.
AC A9UTB3;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 28-JUN-2023, entry version 51.
DE RecName: Full=PH domain-containing protein {ECO:0000259|PROSITE:PS50003};
GN ORFNames=MONBRDRAFT_23409 {ECO:0000313|EMBL:EDQ91216.1};
OS Monosiga brevicollis (Choanoflagellate).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ91216.1, ECO:0000313|Proteomes:UP000001357};
RN [1] {ECO:0000313|EMBL:EDQ91216.1, ECO:0000313|Proteomes:UP000001357}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX PubMed=18273011; DOI=10.1038/nature06617;
RG JGI Sequencing;
RA King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT metazoans.";
RL Nature 451:783-788(2008).
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DR EMBL; CH991545; EDQ91216.1; -; Genomic_DNA.
DR RefSeq; XP_001743638.1; XM_001743586.1.
DR AlphaFoldDB; A9UTB3; -.
DR EnsemblProtists; EDQ91216; EDQ91216; MONBRDRAFT_23409.
DR GeneID; 5889187; -.
DR KEGG; mbr:MONBRDRAFT_23409; -.
DR InParanoid; A9UTB3; -.
DR Proteomes; UP000001357; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0045595; P:regulation of cell differentiation; IBA:GO_Central.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR039680; PLEKHB1/2.
DR PANTHER; PTHR14309; EXPRESSED PROTEIN; 1.
DR PANTHER; PTHR14309:SF10; PH DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001357}.
FT DOMAIN 11..122
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 134..183
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 281..321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 138..157
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 281..302
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 321 AA; 35465 MW; 3A793A48EED00C8B CRC64;
MATPPVAPSQ TRLVQGFLTK RGLKLKTWKL RYFVLFDNRV LCYYKLKDFP TANARLPEPL
GTIDLARPFR LLLGAAIPPV EWPSNASVEA VFGLETAERI FYLVSTREDY PTWAAALHQV
QLVSSAEHFI ASDTPLVPDE NSDATRITSS AEPLNSLDHS SKPEEADALA DHPYLPPNDD
GTVPVMPIYS QVDKTRKAAS PELSLHEAQQ ELQALDLRTR PAPPAEDAPA RRRPAAYENI
DVGRDINFPP AGAPALILEP VGDRAAVARV NYTEVTFDKN QVESNKLRDP PTARTVYSQI
DFDKTMQPAR PPAYESMGGP N
//
