ID   A9UXB8_MONBE            Unreviewed;       469 AA.
AC   A9UXB8;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   RecName: Full=Dynein regulatory complex subunit 2 {ECO:0000256|ARBA:ARBA00040899};
GN   ORFNames=MONBRDRAFT_16305 {ECO:0000313|EMBL:EDQ90361.1};
OS   Monosiga brevicollis (Choanoflagellate).
OC   Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX   NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ90361.1, ECO:0000313|Proteomes:UP000001357};
RN   [1] {ECO:0000313|EMBL:EDQ90361.1, ECO:0000313|Proteomes:UP000001357}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX   PubMed=18273011; DOI=10.1038/nature06617;
RG   JGI Sequencing;
RA   King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA   Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA   Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA   Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA   Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA   McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT   "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT   metazoans.";
RL   Nature 451:783-788(2008).
CC   -!- SUBCELLULAR LOCATION: Cell projection, cilium, flagellum
CC       {ECO:0000256|ARBA:ARBA00004230}. Cytoplasm, cytoskeleton, flagellum
CC       basal body {ECO:0000256|ARBA:ARBA00037841}.
CC   -!- SIMILARITY: Belongs to the DRC2 family.
CC       {ECO:0000256|ARBA:ARBA00038424}.
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DR   EMBL; CH991548; EDQ90361.1; -; Genomic_DNA.
DR   RefSeq; XP_001745128.1; XM_001745076.1.
DR   AlphaFoldDB; A9UXB8; -.
DR   STRING; 81824.A9UXB8; -.
DR   EnsemblProtists; EDQ90361; EDQ90361; MONBRDRAFT_16305.
DR   GeneID; 5890070; -.
DR   KEGG; mbr:MONBRDRAFT_16305; -.
DR   eggNOG; ENOG502QQDD; Eukaryota.
DR   InParanoid; A9UXB8; -.
DR   OMA; EQHFETA; -.
DR   Proteomes; UP000001357; Unassembled WGS sequence.
DR   GO; GO:0005858; C:axonemal dynein complex; IEA:InterPro.
DR   GO; GO:0005930; C:axoneme; IBA:GO_Central.
DR   GO; GO:0031514; C:motile cilium; IEA:UniProtKB-SubCell.
DR   GO; GO:0070286; P:axonemal dynein complex assembly; IBA:GO_Central.
DR   GO; GO:0060285; P:cilium-dependent cell motility; IBA:GO_Central.
DR   GO; GO:0003352; P:regulation of cilium movement; IBA:GO_Central.
DR   InterPro; IPR039505; DRC1/2_N.
DR   InterPro; IPR039750; DRC1/DRC2.
DR   InterPro; IPR029440; DRC1_C.
DR   PANTHER; PTHR21625:SF0; DYNEIN REGULATORY COMPLEX SUBUNIT 2; 1.
DR   PANTHER; PTHR21625; NYD-SP28 PROTEIN; 1.
DR   Pfam; PF14772; NYD-SP28; 1.
DR   Pfam; PF14775; NYD-SP28_assoc; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001357}.
FT   DOMAIN          1..74
FT                   /note="Dynein regulatory complex protein 1/2 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14772"
FT   DOMAIN          356..411
FT                   /note="Dynein regulatory complex protein 1 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14775"
FT   COILED          30..75
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          190..277
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:EDQ90361.1"
SQ   SEQUENCE   469 AA;  53929 MW;  ACC6BFD49A8DBB8B CRC64;
     EKLAREEKYT RAALHKINAQ WMAIMRDAKS DELKREIEIL AQTFERVLDR KEAVLQACIQ
     ELNEAEKQAR LLLQIATRSH MKTLDRVVEF HRETVDHLHG DFTRDLEALR REFMQERKHI
     LGLHQQDMAK LKDIVYAMDI SNDDKVHAEE SEFASRRDEL RSNSLDQKTS LKANLEGQIK
     ELWDEFQAAL QHYETSTAEK RAEFERLRAE DSKAAATIES QMKKLANLRE KIAALKQRLA
     SLSSGTDDRN TELTKEKAAI TEQAHALKAR LKRTRERDRR ALATIAVQAK ECEQKLQAKL
     EAARKVLSLA EVCRKLESDE EKVLPFYADT ITDDEVERLQ NEAAETTQAD AATIVAVAYD
     RRNRRIHTYE ALSNFWKRYN KVLLDKLAVE RERALLEEEN TELRNILKQY LDGISVSEEV
     LAQDNTLLIV NGRTNAPMNV PVGDSRVARA QPTVVEASHA LRTTLRGAR
//