ID A9UXZ4_MONBE Unreviewed; 499 AA.
AC A9UXZ4;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Glycosyltransferase 2-like domain-containing protein {ECO:0000259|Pfam:PF00535};
GN ORFNames=MONBRDRAFT_32151 {ECO:0000313|EMBL:EDQ89771.1};
OS Monosiga brevicollis (Choanoflagellate).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ89771.1, ECO:0000313|Proteomes:UP000001357};
RN [1] {ECO:0000313|EMBL:EDQ89771.1, ECO:0000313|Proteomes:UP000001357}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX PubMed=18273011; DOI=10.1038/nature06617;
RG JGI Sequencing;
RA King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT metazoans.";
RL Nature 451:783-788(2008).
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DR EMBL; CH991549; EDQ89771.1; -; Genomic_DNA.
DR RefSeq; XP_001745193.1; XM_001745141.1.
DR AlphaFoldDB; A9UXZ4; -.
DR EnsemblProtists; EDQ89771; EDQ89771; MONBRDRAFT_32151.
DR GeneID; 5890529; -.
DR KEGG; mbr:MONBRDRAFT_32151; -.
DR eggNOG; KOG3736; Eukaryota.
DR InParanoid; A9UXZ4; -.
DR Proteomes; UP000001357; Unassembled WGS sequence.
DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR GO; GO:0004653; F:polypeptide N-acetylgalactosaminyltransferase activity; IBA:GO_Central.
DR GO; GO:0006493; P:protein O-linked glycosylation; IBA:GO_Central.
DR CDD; cd00161; RICIN; 1.
DR Gene3D; 2.80.10.50; -; 1.
DR InterPro; IPR001173; Glyco_trans_2-like.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR InterPro; IPR035992; Ricin_B-like_lectins.
DR InterPro; IPR000772; Ricin_B_lectin.
DR PANTHER; PTHR11675; N-ACETYLGALACTOSAMINYLTRANSFERASE; 1.
DR PANTHER; PTHR11675:SF43; POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 1; 1.
DR Pfam; PF00535; Glycos_transf_2; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR SUPFAM; SSF50370; Ricin B-like lectins; 1.
DR PROSITE; PS50231; RICIN_B_LECTIN; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Lectin {ECO:0000256|ARBA:ARBA00022734}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001357};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 48..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 166..343
FT /note="Glycosyltransferase 2-like"
FT /evidence="ECO:0000259|Pfam:PF00535"
SQ SEQUENCE 499 AA; 55009 MW; BD2F9D45BD430E42 CRC64;
MAARTYHDGS YGQRAVYGQV KVPPLPVFHE HKPVKPVSSR RCRGPSGVGL LLLAGGTLFI
CALLVLLNTI SEGPAAPRIL KETQLVRAEE RFAAPQAAAH KAIIDEWKNK KLTSEQEQIR
AQGYQRNAFN QMISDLLPLD REFGDHRPDE CLAQWYLPPS ELPTTSVIII FHNEAISTLL
RTVHSVLNRS PSALIAEVLL VDDASTGEWL DASFEAQVAA IPKARLMRLP ERSGLIRAKI
AGARQARGEV ILFLDSHCEV NPGWLQPMLH RLREEPNAIV CPVIDIIKSD DFSYVPVSAT
TQIGVFTWFM QFSWSELTEQ QQAARPSSVA PIPSPTMAGG LFAMRKILET YLIVLNSASN
CVVAHFQSTS FSTAPVSSAF LIIATCGRNP SSGECLVLTT TNYDSVRDVK MRCLVPESST
ATKIVLDNCN ENGRFALDLG WLEWKHLQTG QVYHPATNRC IGMIANNGTS NSEVGLVSCS
KSAKQQWTFT EFSDIEYSS
//
