ID A9V076_MONBE Unreviewed; 1418 AA.
AC A9V076;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=OBG-type G domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=MONBRDRAFT_32543 {ECO:0000313|EMBL:EDQ88962.1};
OS Monosiga brevicollis (Choanoflagellate).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ88962.1, ECO:0000313|Proteomes:UP000001357};
RN [1] {ECO:0000313|EMBL:EDQ88962.1, ECO:0000313|Proteomes:UP000001357}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX PubMed=18273011; DOI=10.1038/nature06617;
RG JGI Sequencing;
RA King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT metazoans.";
RL Nature 451:783-788(2008).
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DR EMBL; CH991552; EDQ88962.1; -; Genomic_DNA.
DR RefSeq; XP_001746067.1; XM_001746015.1.
DR STRING; 81824.A9V076; -.
DR EnsemblProtists; EDQ88962; EDQ88962; MONBRDRAFT_32543.
DR GeneID; 5891483; -.
DR KEGG; mbr:MONBRDRAFT_32543; -.
DR eggNOG; KOG1491; Eukaryota.
DR InParanoid; A9V076; -.
DR Proteomes; UP000001357; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IBA:GO_Central.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR Gene3D; 1.10.8.470; -; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 2.60.40.1400; G protein-activated inward rectifier potassium channel 1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR005645; FSH-like_dom.
DR InterPro; IPR031167; G_OBG.
DR InterPro; IPR006073; GTP-bd.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR006575; RWD_dom.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR InterPro; IPR013646; YGR210-like_G4.
DR PANTHER; PTHR23305; OBG GTPASE FAMILY; 1.
DR PANTHER; PTHR23305:SF1; OBG-TYPE G DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF03959; FSH1; 1.
DR Pfam; PF01926; MMR_HSR1; 1.
DR Pfam; PF05773; RWD; 1.
DR Pfam; PF08438; YGR210-like_G4; 1.
DR PRINTS; PR00326; GTP1OBG.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54495; UBC-like; 1.
DR PROSITE; PS51710; G_OBG; 1.
DR PROSITE; PS50908; RWD; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001357};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 132..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 744..856
FT /note="RWD"
FT /evidence="ECO:0000259|PROSITE:PS50908"
FT DOMAIN 932..1243
FT /note="OBG-type G"
FT /evidence="ECO:0000259|PROSITE:PS51710"
FT REGION 1..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 467..502
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 870..891
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 27..43
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 469..502
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1418 AA; 155429 MW; 7070D086EA67A55C CRC64;
MTSEEAPLPS RAQSEAEAKG RRTKDGPENG SASSSEHIGL SDSMSSDLDI NTADAISDPQ
TLHRKESILA CKLRVKRRME RMRRNSKIRK LPKHTSGSQW YQVVKGRITM LNKQFSSQFN
LIFISLELSW RWLLLSYFIT IFLLALVLAG LFEAGHCVDQ LDFDVVYLIV AQQLMTGPSF
IEMTDKDFIE LDSGCWFLAF ISSCCTLFLQ AFVLSMAVRK FMKPRSAIAF SKKLCFNSRN
GIPCLQTRMM NLRGNLISDL QIRASWSYPV KTLEGEQHWR IETLNFAGPL FIKLPGRLYM
EVIGYDHVLC EEVHTTWAFQ LPEDTAPYCR FADMVVKSFQ ESVQDKTFKP MLEMGNFECV
EPVLLDLDET GRCPTLRCRK CHVHVRCCNG LVAAVPLIWK ALQTWAWSHN QFPRSDMESE
RERQALLKLS TAARSLQDDR ETGSSLCAGV TESLAAAAAS PAMDAPQALH GSSLSQPSDT
LTTELDSSAP NAPSTNNDAQ AWSEPQSQRA EGVCVCVCVC VCVCVCVCVC VCVCVCDPPI
QRARYYCPWK QATTFQLAPG LMTTLVSKSR RINASLASAD EPILLLAFSQ GCYVATMLIW
LLEELDRDLQ SPSVEPALQV ALAPLLAHPR IAVFVGAPDE GFPADWLASQ PTFAAPHPQA
RMYTRSFHLM GTRDDLVKPE SSRRFATRFH DPVCIEHGAG HVVPAARNVW DPIVNAIAAL
AKPAPSQHTP PAPNQFEATE EQREELEGLG AIFDTDFELE SQRPPSYSII LRTALETDHY
QAHPARLYVT LTQAYPETAP VARVVGVCSA LQVPQNLMPV VEGQLAAALE ASISENLGAE
MGMQLVDAAS QALQEAAEDL TTGKLLQADT HHSQTETGPS AEILPGQQLR GDVDDLPPEE
VDELIHQATA AAAAVDNAAA HPISYGGGAW RYTIGLVGKP SAGKSTLFNA ITDPKTADAT
ARVAAFPFTT IDPNIGQGYY CASCPSAVLS CESEPAHGWG AGHKQRKIPI IIKDVAGLVP
GAYQGRGKGN AFLNDLCDAD VLIHVIDASG TSDRDGVTGD AEAGDPCDDV TWVREELHRW
IYNNVRAKWH TVLRERVEPV LSNCVNYDCL TTESSCGDRK TERLYNLFTG YHCKRAHVDE
ALRRAGHVVD EANMGLSALK LLCVHQELGA ALAAWGPRDL HGLIAHFLRV RFPILLAMNK
VDVSTEHVAR LEAQFPSDRK LPMVARAEWD LCQLRRQGFV SYATGADSFS ISSMAPKDTL
QGRLEDIRAC MEAVQKAVKD TGAPMGASNP LSTGVLAVVN AAVALKPPLV VYPVLSLQAL
TSVLSDEEHG ARTCLGECLL LHPGTTVEGL YDCLRRPPLN AIQGEFVRAE CLDMGQRDAG
ASAFHGFATR PLRKTAVLTP DTCIVHVMTN RKNTRQGR
//
