ID A9V255_MONBE Unreviewed; 192 AA.
AC A9V255;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=SH2 domain-containing protein {ECO:0000259|PROSITE:PS50001};
GN ORFNames=MONBRDRAFT_9122 {ECO:0000313|EMBL:EDQ88194.1};
OS Monosiga brevicollis (Choanoflagellate).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ88194.1, ECO:0000313|Proteomes:UP000001357};
RN [1] {ECO:0000313|EMBL:EDQ88194.1, ECO:0000313|Proteomes:UP000001357}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX PubMed=18273011; DOI=10.1038/nature06617;
RG JGI Sequencing;
RA King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT metazoans.";
RL Nature 451:783-788(2008).
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DR EMBL; CH991555; EDQ88194.1; -; Genomic_DNA.
DR RefSeq; XP_001746787.1; XM_001746735.1.
DR AlphaFoldDB; A9V255; -.
DR STRING; 81824.A9V255; -.
DR EnsemblProtists; EDQ88194; EDQ88194; MONBRDRAFT_9122.
DR GeneID; 5892234; -.
DR KEGG; mbr:MONBRDRAFT_9122; -.
DR eggNOG; KOG0790; Eukaryota.
DR InParanoid; A9V255; -.
DR OMA; VERFMNG; -.
DR Proteomes; UP000001357; Unassembled WGS sequence.
DR GO; GO:0005942; C:phosphatidylinositol 3-kinase complex; IBA:GO_Central.
DR GO; GO:0046935; F:1-phosphatidylinositol-3-kinase regulator activity; IBA:GO_Central.
DR GO; GO:0046854; P:phosphatidylinositol phosphate biosynthetic process; IBA:GO_Central.
DR CDD; cd00173; SH2; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR PANTHER; PTHR10155; PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR10155:SF10; PI3K21B, ISOFORM B; 1.
DR Pfam; PF00017; SH2; 1.
DR PRINTS; PR00401; SH2DOMAIN.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS50001; SH2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001357};
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT DOMAIN 4..102
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT REGION 165..192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 192 AA; 20986 MW; 75D407C742C8756F CRC64;
MARYYHGRIT REEAVDRLLK EGVDGSFLLR MSTTQDGVYT LSLMQGESVR HIRIVNTIDG
GYAISAGDPG VDSVWQLVET QMHNTLTSAY DRSDQVALRY PLKANGDVIA PDLLMSAGEA
GIDAADFGDD VAAFLEGGVD AKALARQRSV KMSVRRPKDL KVASHDDPFA GLELPSDFDP
DNLPENYIVP ED
//
