ID A9V4B8_MONBE Unreviewed; 586 AA.
AC A9V4B8;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=Carbohydrate kinase PfkB domain-containing protein {ECO:0000259|Pfam:PF00294};
GN ORFNames=MONBRDRAFT_27110 {ECO:0000313|EMBL:EDQ87683.1};
OS Monosiga brevicollis (Choanoflagellate).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ87683.1, ECO:0000313|Proteomes:UP000001357};
RN [1] {ECO:0000313|EMBL:EDQ87683.1, ECO:0000313|Proteomes:UP000001357}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX PubMed=18273011; DOI=10.1038/nature06617;
RG JGI Sequencing;
RA King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT metazoans.";
RL Nature 451:783-788(2008).
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DR EMBL; CH991558; EDQ87683.1; -; Genomic_DNA.
DR RefSeq; XP_001747603.1; XM_001747551.1.
DR AlphaFoldDB; A9V4B8; -.
DR STRING; 81824.A9V4B8; -.
DR EnsemblProtists; EDQ87683; EDQ87683; MONBRDRAFT_27110.
DR GeneID; 5892849; -.
DR KEGG; mbr:MONBRDRAFT_27110; -.
DR eggNOG; KOG3009; Eukaryota.
DR InParanoid; A9V4B8; -.
DR Proteomes; UP000001357; Unassembled WGS sequence.
DR GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004730; F:pseudouridylate synthase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.1190.20; -; 1.
DR Gene3D; 3.40.1790.10; Indigoidine synthase domain; 2.
DR InterPro; IPR002173; Carboh/pur_kinase_PfkB_CS.
DR InterPro; IPR022830; Indigdn_synthA-like.
DR InterPro; IPR011611; PfkB_dom.
DR InterPro; IPR007342; PsuG.
DR InterPro; IPR029056; Ribokinase-like.
DR PANTHER; PTHR42909:SF1; PFKB DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR42909; ZGC:136858; 1.
DR Pfam; PF04227; Indigoidine_A; 2.
DR Pfam; PF00294; PfkB; 1.
DR SUPFAM; SSF110581; Indigoidine synthase A-like; 1.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
DR PROSITE; PS00584; PFKB_KINASES_2; 1.
PE 4: Predicted;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001357};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 507..566
FT /note="Carbohydrate kinase PfkB"
FT /evidence="ECO:0000259|Pfam:PF00294"
SQ SEQUENCE 586 AA; 62465 MW; 12D1B2DA02E8FAE4 CRC64;
MLLWAVGRGQ AVVAGRRALT REATPKWLNI SEEVQQALVE DQAVVALEST IISHGMPYPT
NLEVAHAVEQ DIRQNGAVPA TIALARGQVH VGLSKALLEE LADPNAKVQK TSRRDLAQVL
SQGQLGSTTV AGTMIAAHAA GIDVFATGGI GGVHRDGENT MDVSADLTEL GRTPVAVICA
GVKSILDIPH VDAAIEAGLA AAKASNVMGK DVTPFLLSYV NQATAGRSLQ ANIALVRNNA
ATAARIAVAA RMPGSRRDMS THAGLGRAYV LGGATEDVLC RTDRRAEASY NTSRHFTWYG
IACVSCAWIR DVSLAQVLPA SRTATYAAFL ERGALVSAIA DMDVMQQLLR FQQFPKLETQ
DIILLDANGL GDHLDATVRG PLEAWLAQHR VWLEPTSTVR AIEAGRLTTR IPIWAISPDF
QEFGVLLEQL SRSAAHDYAA LDPADTESTL DFVQTRWTRL FADHTPHGRA PLLFLKRGAQ
GLIAPDVATL QAWADPSRTT SPTTPHVYQH FCPEPVTQIV NVTGAGDSMV AAILAMLLAR
RYDSAVAVGL RAARLSLAFT GAINPASSQL RDCVVHGAGL SDQPVL
//
