ID A9V7P9_MONBE Unreviewed; 664 AA.
AC A9V7P9;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 24-JAN-2024, entry version 67.
DE RecName: Full=PDZ domain-containing protein {ECO:0000259|PROSITE:PS50106};
GN ORFNames=MONBRDRAFT_28279 {ECO:0000313|EMBL:EDQ86343.1};
OS Monosiga brevicollis (Choanoflagellate).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ86343.1, ECO:0000313|Proteomes:UP000001357};
RN [1] {ECO:0000313|EMBL:EDQ86343.1, ECO:0000313|Proteomes:UP000001357}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX PubMed=18273011; DOI=10.1038/nature06617;
RG JGI Sequencing;
RA King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT metazoans.";
RL Nature 451:783-788(2008).
CC -!- SIMILARITY: Belongs to the peptidase S1C family.
CC {ECO:0000256|ARBA:ARBA00010541}.
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DR EMBL; CH991566; EDQ86343.1; -; Genomic_DNA.
DR RefSeq; XP_001748733.1; XM_001748681.1.
DR AlphaFoldDB; A9V7P9; -.
DR STRING; 81824.A9V7P9; -.
DR MEROPS; S01.279; -.
DR EnsemblProtists; EDQ86343; EDQ86343; MONBRDRAFT_28279.
DR GeneID; 5894065; -.
DR KEGG; mbr:MONBRDRAFT_28279; -.
DR eggNOG; KOG1320; Eukaryota.
DR InParanoid; A9V7P9; -.
DR OMA; CVEHNTQ; -.
DR Proteomes; UP000001357; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IBA:GO_Central.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd00987; PDZ_serine_protease; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 3.20.190.20; -; 1.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR InterPro; IPR041517; DEGP_PDZ.
DR InterPro; IPR046449; DEGP_PDZ_sf.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001940; Peptidase_S1C.
DR PANTHER; PTHR45980; -; 1.
DR PANTHER; PTHR45980:SF9; PROTEASE DO-LIKE 10, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF13180; PDZ_2; 1.
DR Pfam; PF17815; PDZ_3; 1.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001357}.
FT DOMAIN 380..448
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 642..664
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 664 AA; 72268 MW; D2657D0A4655AC22 CRC64;
MTTIRITMRK CDIFYSTSEQ MLMLSLSLSL SLSLSLSLSL SLSLSLSLSL CVVFARVSVA
VTVAAAGGRD GASVFCDACR LAPVYPKGLF QAPTLGTVAS FRPVRYHLRP SLARLSVTAA
MTRRGAANAA AAKESRQQRL TLKRPSAPRL VMTSKSKGAA PATASVDGIP QGITHKLPVG
SVVKIFTVTS KPNYLLPWQM GGPDACSGSG FLVAGRRIIT NAHVVSNYTQ VRVRKHGGQF
KYLARVLCIN HTCDLALLEI DSDEFWEGVE QLQINTDIPD LDERVVVLGY PMGGDTLSLT
RGVVSRVTTL NYEEVKFQPR HGPELLAIQI DAAINSGNSG GPVFRENGDI VGVAFSGYAG
SADNIGYIIP TPVITSFLTS INTNGTSAGV CDIGIRYELC ENPSMQRKLK MEQHSGIHVI
KVAQLGPAAG KVKVGDVITK INDYPVANDG TIPFRGEERV SVQHAISSHP LGKTMKMVVL
RDSELVNLEL EGAVTPPLVE CYREVGTMPS YFIFGGCLFS PMTSGLIEPC IDDFDDESWE
ASRKAKTHED EQIVVMVSVL SHPINHGYNM SRIRRIHKCN NTVIRNLQHL KQLVDESDKY
VHFELSIGKN IILDKAECLE AEREILKTYA VPAPCSRDLL SEKEQEALTP RNGGARSKRA
KRAK
//
