ID A9WAR3_CHLAA Unreviewed; 227 AA.
AC A9WAR3;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Phospholipid/glycerol acyltransferase {ECO:0000313|EMBL:ABY33291.1};
GN OrderedLocusNames=Caur_0036 {ECO:0000313|EMBL:ABY33291.1};
OS Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl).
OC Bacteria; Chloroflexota; Chloroflexia; Chloroflexales; Chloroflexineae;
OC Chloroflexaceae; Chloroflexus.
OX NCBI_TaxID=324602 {ECO:0000313|EMBL:ABY33291.1, ECO:0000313|Proteomes:UP000002008};
RN [1] {ECO:0000313|Proteomes:UP000002008}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29366 / DSM 635 / J-10-fl
RC {ECO:0000313|Proteomes:UP000002008};
RX PubMed=21714912; DOI=10.1186/1471-2164-12-334;
RA Tang K.H., Barry K., Chertkov O., Dalin E., Han C.S., Hauser L.J.,
RA Honchak B.M., Karbach L.E., Land M.L., Lapidus A., Larimer F.W.,
RA Mikhailova N., Pitluck S., Pierson B.K., Blankenship R.E.;
RT "Complete genome sequence of the filamentous anoxygenic phototrophic
RT bacterium Chloroflexus aurantiacus.";
RL BMC Genomics 12:334-334(2011).
CC -!- FUNCTION: Converts lysophosphatidic acid (LPA) into phosphatidic acid
CC by incorporating acyl moiety at the 2 position.
CC {ECO:0000256|ARBA:ARBA00037183}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-
CC sn-glycero-3-phosphate + CoA; Xref=Rhea:RHEA:19709,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57970, ChEBI:CHEBI:58342,
CC ChEBI:CHEBI:58608; EC=2.3.1.51;
CC Evidence={ECO:0000256|ARBA:ARBA00001141};
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DR EMBL; CP000909; ABY33291.1; -; Genomic_DNA.
DR RefSeq; WP_012255947.1; NC_010175.1.
DR RefSeq; YP_001633680.1; NC_010175.1.
DR AlphaFoldDB; A9WAR3; -.
DR STRING; 324602.Caur_0036; -.
DR EnsemblBacteria; ABY33291; ABY33291; Caur_0036.
DR KEGG; cau:Caur_0036; -.
DR PATRIC; fig|324602.8.peg.40; -.
DR eggNOG; COG0204; Bacteria.
DR HOGENOM; CLU_027938_4_5_0; -.
DR InParanoid; A9WAR3; -.
DR Proteomes; UP000002008; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003841; F:1-acylglycerol-3-phosphate O-acyltransferase activity; IBA:GO_Central.
DR GO; GO:0006654; P:phosphatidic acid biosynthetic process; IBA:GO_Central.
DR CDD; cd07989; LPLAT_AGPAT-like; 1.
DR InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR PANTHER; PTHR10434; 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE; 1.
DR PANTHER; PTHR10434:SF60; 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE LPAT1, CHLOROPLASTIC; 1.
DR Pfam; PF01553; Acyltransferase; 1.
DR SMART; SM00563; PlsC; 1.
DR SUPFAM; SSF69593; Glycerol-3-phosphate (1)-acyltransferase; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000313|EMBL:ABY33291.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002008};
KW Transferase {ECO:0000313|EMBL:ABY33291.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 41..155
FT /note="Phospholipid/glycerol acyltransferase"
FT /evidence="ECO:0000259|SMART:SM00563"
SQ SEQUENCE 227 AA; 25411 MW; 14E20C9DF74F1D4B CRC64;
MFAYVVYGIL YLIINFFRLI GWWRWSISGI ERLPPREQGG MILVMNHINW VDIPAVGAML
PFRYRLSWLA KIEIFSHPLA GWFFRNMDVI PIRRGKRDLA ALDAAAQALR NGAVLLIFPE
GHRSRNGILQ PGRGGAVRLA MQAGVPLVPM AITGTEHGFR GTLLRKPVHI TIGEPYRVEP
LPDNKIPADV MEQLTNEMML KIAAMLPPAQ RGPYAALLEA AAVKEQV
//
