ID A9X170_PAPAN Unreviewed; 325 AA.
AC A9X170;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 22-FEB-2023, entry version 51.
DE SubName: Full=MCF.2 cell line derived transforming sequence-like (Predicted), 3 prime {ECO:0000313|EMBL:ABY40833.1};
DE Flags: Fragment;
GN Name=MCF2L {ECO:0000313|EMBL:ABY40833.1};
OS Papio anubis (Olive baboon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Papio.
OX NCBI_TaxID=9555 {ECO:0000313|EMBL:ABY40833.1};
RN [1] {ECO:0000313|EMBL:ABY40833.1}
RP NUCLEOTIDE SEQUENCE.
RA Antonellis A., Benjamin B., Blakesley R.W., Bouffard G.G., Brinkley C.,
RA Brooks S., Chu G., Chub I., Coleman H., Fuksenko T., Gestole M.,
RA Gregory M., Guan X., Gupta J., Gurson N., Han E., Han J., Hansen N.,
RA Hargrove A., Hines-Harris K., Ho S.-L., Hu P., Hunter G., Hurle B.,
RA Idol J.R., Johnson T., Knight E., Kwong P., Lee-Lin S.-Q., Legaspi R.,
RA Madden M., Maduro Q.L., Maduro V.B., Margulies E.H., Masiello C.,
RA Maskeri B., McDowell J., Merkulov G., Montemayor C., Mullikin J.C.,
RA Park M., Prasad A., Ramsahoye C., Reddix-Dugue N., Riebow N., Schandler K.,
RA Schueler M.G., Sison C., Smith L., Stantripop S., Thomas J.W., Thomas P.J.,
RA Tsipouri V., Young A., Green E.D.;
RT "NISC Comparative Sequencing Initiative.";
RL Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DP000536; ABY40833.1; -; Genomic_DNA.
DR AlphaFoldDB; A9X170; -.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd01227; PH_Dbs; 1.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR035534; DBS_PH.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR001331; GDS_CDC24_CS.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR22826:SF115; GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS; 1.
DR PANTHER; PTHR22826; RHO GUANINE EXCHANGE FACTOR-RELATED; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS00741; DH_1; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
FT DOMAIN 1..94
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 112..228
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 292..311
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ABY40833.1"
SQ SEQUENCE 325 AA; 36753 MW; 7FB4041B51352337 CRC64;
MEDFQIYEKY CQNKPRSESL WRQCSDCPFF QECQRKLDHK LSLDSYLLKP VQRITKYQLL
LKEMLKYSKN CEGAEDLQEA LSSILGILKA VNDSMHLIAI TGYDGNLGDL GKLLMQGSFS
VWTDHKRGHT KVKELARFKP MQRHLFLHEK AVLFCKKREE NGEGYEKAPS YSYKQSLNMA
AVGITENVKG DAKKFEIWYN AREEVYIVQA PTPEIKAAWV NEIRKVLTSQ LQACRGEAVF
KPSFSCSFLS RCIFTCVQSN RTVPVCARRL GAEVKTLIHV VCLLPPRRSQ PAPGTGAVAE
PAPAGPDQHQ VRTDTAPQAC VYGAL
//
