ID AAEA_YERPP Reviewed; 311 AA.
AC A4THE9;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 15-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE RecName: Full=p-hydroxybenzoic acid efflux pump subunit AaeA {ECO:0000255|HAMAP-Rule:MF_01544};
DE Short=pHBA efflux pump protein A {ECO:0000255|HAMAP-Rule:MF_01544};
GN Name=aaeA {ECO:0000255|HAMAP-Rule:MF_01544}; OrderedLocusNames=YPDSF_0292;
OS Yersinia pestis (strain Pestoides F).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=386656;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pestoides F;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Di Bartolo G., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA Larimer F., Land M., Hauser L., Worsham P., Chu M., Bearden S., Garcia E.,
RA Richardson P.;
RT "Complete sequence of chromosome of Yersinia pestis Pestoides F.";
RL Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Forms an efflux pump with AaeB. {ECO:0000255|HAMAP-
CC Rule:MF_01544}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01544}; Single-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01544}.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000255|HAMAP-Rule:MF_01544}.
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DR EMBL; CP000668; ABP38711.1; -; Genomic_DNA.
DR RefSeq; WP_002210094.1; NZ_CP009715.1.
DR AlphaFoldDB; A4THE9; -.
DR SMR; A4THE9; -.
DR GeneID; 66844034; -.
DR KEGG; ypp:YPDSF_0292; -.
DR PATRIC; fig|386656.14.peg.1591; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR HAMAP; MF_01544; AaeA; 1.
DR InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR InterPro; IPR022871; PHBA_efflux_pump_AaeA.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30367:SF12; P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT AAEA; 1.
DR PANTHER; PTHR30367; P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT AAEA-RELATED; 1.
DR Pfam; PF13533; Biotin_lipoyl_2; 1.
DR Pfam; PF13437; HlyD_3; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..311
FT /note="p-hydroxybenzoic acid efflux pump subunit AaeA"
FT /id="PRO_0000300561"
FT TRANSMEM 11..31
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01544"
SQ SEQUENCE 311 AA; 34315 MW; 8735684261C3CC00 CRC64;
MSTFSLKIIR VGITVLVVVL AVIAIFNVWA FYTESPWTRD AKFTADVVAI APDVSGLLTE
VPVKDNQLVQ KGQILFVIDQ PRYQQALAEA EADVAYYQTL AAEKQRESSR RHRLGIQALS
QEEIDQASNV LQTVQHQLAK AIAVRDLARL DLERTTVRAP AEGWVTNLNV HAGEFINRGA
TAVALVKKDT FYILAYLEET KLEGVKPGYR AEITPLGSNR ILHGTVDSIS AGVTNSSSSA
DSKGLATIDN NLEWVRLAQR VPVKIHLDSE DQQYLYPAGT TATVVITGPN DRDPHQASPM
TKLMHRLREF G
//
