ID ANM1_ORYSJ Reviewed; 387 AA.
AC Q0J2C6; A3BY04; B7EPL4; Q6K563;
DT 10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 03-OCT-2006, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE RecName: Full=Probable protein arginine N-methyltransferase 1;
DE EC=2.1.1.-;
GN Name=PRMT1; OrderedLocusNames=Os09g0359800, LOC_Os09g19560;
GN ORFNames=OsJ_027926, P0711F01.27-1;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
CC -!- FUNCTION: Methylates (mono and asymmetric dimethylation) the guanidino
CC nitrogens of arginyl residues present in a glycine and arginine-rich
CC domain (can methylate histones). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. Protein arginine N-methyltransferase family.
CC {ECO:0000255|PROSITE-ProRule:PRU01015}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAD23315.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=EAZ44443.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AP005508; BAD23315.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP008215; BAF24889.1; -; Genomic_DNA.
DR EMBL; AP014965; BAT07684.1; -; Genomic_DNA.
DR EMBL; CM000146; EAZ44443.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AK099826; BAG94311.1; -; mRNA.
DR RefSeq; XP_015612441.1; XM_015756955.1.
DR AlphaFoldDB; Q0J2C6; -.
DR SMR; Q0J2C6; -.
DR STRING; 39947.Q0J2C6; -.
DR PaxDb; 39947-Q0J2C6; -.
DR EnsemblPlants; Os09t0359800-01; Os09t0359800-01; Os09g0359800.
DR GeneID; 4346843; -.
DR Gramene; Os09t0359800-01; Os09t0359800-01; Os09g0359800.
DR KEGG; osa:4346843; -.
DR eggNOG; KOG1499; Eukaryota.
DR HOGENOM; CLU_017375_1_2_1; -.
DR InParanoid; Q0J2C6; -.
DR OMA; GFWDNVW; -.
DR OrthoDB; 197898at2759; -.
DR Proteomes; UP000000763; Chromosome 9.
DR Proteomes; UP000007752; Chromosome 9.
DR Proteomes; UP000059680; Chromosome 9.
DR ExpressionAtlas; Q0J2C6; baseline and differential.
DR Genevisible; Q0J2C6; OS.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0016274; F:protein-arginine N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 2.70.160.11; Hnrnp arginine n-methyltransferase1; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR025799; Arg_MeTrfase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR11006:SF53; ARGININE METHYLTRANSFERASE 1-RELATED; 1.
DR PANTHER; PTHR11006; PROTEIN ARGININE N-METHYLTRANSFERASE; 1.
DR Pfam; PF06325; PrmA; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51678; SAM_MT_PRMT; 1.
PE 2: Evidence at transcript level;
KW Methyltransferase; Nucleus; Reference proteome; S-adenosyl-L-methionine;
KW Transferase.
FT CHAIN 1..387
FT /note="Probable protein arginine N-methyltransferase 1"
FT /id="PRO_0000293989"
FT DOMAIN 66..387
FT /note="SAM-dependent MTase PRMT-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01015"
FT REGION 1..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 178
FT /evidence="ECO:0000250"
FT ACT_SITE 187
FT /evidence="ECO:0000250"
SQ SEQUENCE 387 AA; 43014 MW; DB36D4628EF4BA63 CRC64;
MDQRKGSGSD ANGGLAEATA SRLRFEDPDE VMEENPAAAA ATVGAEEEGG EGGGGEEVIG
SDKTSADYYF DSYSHFGIHE EMLKDVVRTK SYQNVITQNS FLFKDKIVLD VGAGTGILSL
FCAKAGAKHV YAIECSQMAD MAKEIVKTNG YSNVITVIKG KVEEIELPVP KVDVIISEWM
GYFLLFENML NTVLYARDKW LADGGVVLPD KASLHLTAIE DAEYKEDKIE FWNNVYGFDM
RCIKKQAMME PLVDTVDANQ IVTNCQLLKT MDISKMTPGD ASFTVPFKLV AERNDYIHAL
VAYFNVSFTK CHKMMGFSTG PRSKATHWKQ TVLYLEDVLT ICEGETITGS MTVTPNKKNP
RDIDIKLCYA LSGHRCQVSR TQHYKMR
//
