ID ARGP_PSEF5 Reviewed; 299 AA.
AC Q4K779;
DT 31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 02-AUG-2005, sequence version 1.
DT 27-MAR-2024, entry version 105.
DE RecName: Full=HTH-type transcriptional regulator ArgP {ECO:0000255|HAMAP-Rule:MF_00513};
GN Name=argP {ECO:0000255|HAMAP-Rule:MF_00513}; Synonyms=iciA;
GN OrderedLocusNames=PFL_4823;
OS Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=220664;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-477 / NRRL B-23932 / Pf-5;
RX PubMed=15980861; DOI=10.1038/nbt1110;
RA Paulsen I.T., Press C.M., Ravel J., Kobayashi D.Y., Myers G.S.A.,
RA Mavrodi D.V., DeBoy R.T., Seshadri R., Ren Q., Madupu R., Dodson R.J.,
RA Durkin A.S., Brinkac L.M., Daugherty S.C., Sullivan S.A., Rosovitz M.J.,
RA Gwinn M.L., Zhou L., Schneider D.J., Cartinhour S.W., Nelson W.C.,
RA Weidman J., Watkins K., Tran K., Khouri H., Pierson E.A., Pierson L.S. III,
RA Thomashow L.S., Loper J.E.;
RT "Complete genome sequence of the plant commensal Pseudomonas fluorescens
RT Pf-5.";
RL Nat. Biotechnol. 23:873-878(2005).
CC -!- FUNCTION: Controls the transcription of genes involved in arginine and
CC lysine metabolism. {ECO:0000255|HAMAP-Rule:MF_00513}.
CC -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00513}.
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000305}.
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DR EMBL; CP000076; AAY94053.1; -; Genomic_DNA.
DR RefSeq; WP_011063077.1; NC_004129.6.
DR AlphaFoldDB; Q4K779; -.
DR SMR; Q4K779; -.
DR STRING; 220664.PFL_4823; -.
DR KEGG; pfl:PFL_4823; -.
DR PATRIC; fig|220664.5.peg.4935; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_063829_0_0_6; -.
DR Proteomes; UP000008540; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.190.290; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR HAMAP; MF_00513; HTH_type_ArgP; 1.
DR InterPro; IPR017685; ArgP.
DR InterPro; IPR023490; ArgP_gammaproteobact.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR03298; argP; 1.
DR PANTHER; PTHR30579:SF2; HTH-TYPE TRANSCRIPTIONAL REGULATOR ARGP; 1.
DR PANTHER; PTHR30579; TRANSCRIPTIONAL REGULATOR; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW DNA-binding; Transcription; Transcription regulation.
FT CHAIN 1..299
FT /note="HTH-type transcriptional regulator ArgP"
FT /id="PRO_0000258610"
FT DOMAIN 2..58
FT /note="HTH lysR-type"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00513"
FT DNA_BIND 19..38
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00513"
SQ SEQUENCE 299 AA; 33223 MW; 5E4402C6E3ACB937 CRC64;
MFDYKLLSAL AAVIEQAGFE RAAQVLGLSQ SAISQRIKLL EARVGQPVLV RVTPPAPTEI
GRRLLNHVQQ VRLLERDLQS LVPALDEEGL PERLRIALNA DSLATWWAGA VGDFCAEHHL
LLDLVVEDQT VGLKRMRAGE VAACVCASER PVAGARSLLL GAMRYRAMAS PEFIVRHFPQ
GVRAEQLPRT PALVFGPDDF LQHRYLASLG VDGAFEHHLC PSSEGFIRLT EAGLGWGLVP
ELQVREQLER GLLLELLPDK PIDVPLYWHH WRNGGQLLGL LTEHLARLSA QWLVPWEQP
//
